Evidence map›Paper›PMID 37591545›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2023

In Vivo Cerebral Imaging of Mutant Huntingtin Aggregates Using

Daniele Bertoglio, Alison R Weiss, William Liguore, Lauren Drew Martin, Theodore Hobbs, John Templon, Sathya Srinivasan, Celia Dominguez, Ignacio Munoz-Sanjuan, Vinod Khetarpal and 6 more

Abstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. In Vivo PET Imaging of [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  4. Preclinical evaluation of [Journal of molecular medicine (Berlin, Germany) · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Preclinical evaluation of the novel [European journal of nuclear medicine and molecular imaging · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Daniele BertoglioBio-Imaging Lab, University of Antwerp, Antwerp, Belgium; daniele.bertoglio@uantwerpen.be weissa@ohsu.edu.
Alison R WeissDivision of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon; daniele.bertoglio@uantwerpen.be weissa@ohsu.edu.
William LiguoreDivision of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon.
Lauren Drew MartinDivision of Animal Resources and Research Support, Oregon National Primate Research Center, Beaverton, Oregon.
Theodore HobbsDivision of Animal Resources and Research Support, Oregon National Primate Research Center, Beaverton, Oregon.
John TemplonCenter for Radiochemistry Research, Oregon Health and Science University, Portland, Oregon.
Sathya SrinivasanIntegrated Pathology Core, Oregon National Primate Research Center, Beaverton, Oregon.
Celia DominguezCHDI Management/CHDI Foundation, Los Angeles, California; and.
Ignacio Munoz-SanjuanCHDI Management/CHDI Foundation, Los Angeles, California; and.
Vinod KhetarpalCHDI Management/CHDI Foundation, Los Angeles, California; and.
Jeroen VerhaegheMolecular Imaging Center Antwerp, University of Antwerp, Antwerp, Belgium.
Steven StaelensMolecular Imaging Center Antwerp, University of Antwerp, Antwerp, Belgium.
Jeanne LinkCenter for Radiochemistry Research, Oregon Health and Science University, Portland, Oregon.
Longbin LiuCHDI Management/CHDI Foundation, Los Angeles, California; and.
Jonathan A BardCHDI Management/CHDI Foundation, Los Angeles, California; and.
Jodi L McBrideDivision of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon.

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
Neuroscience of Aging, Neurodegeneration and Alzheimer’s DiseaseT32AG055378 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI JACOB RABER, HENRYK F URBANSKI · 2018 to 2026
$4.3M
NIA NIH HHS T32 AG055378NIH HHS P51 OD011092
6 · The paper itself

Abstract

Huntington disease (HD) is a neurodegenerative disorder caused by an expanded polyglutamine (CAG) trinucleotide expansion in the huntingtin (

Indexed as

Huntington DiseaseAnimalsDisease Models, AnimalHuntingtin ProteinMacaca mulattaNerve Tissue ProteinsPositron-Emission TomographyPositron Emission Tomography Computed TomographyHuntingtin ProteinNerve Tissue ProteinsbrainHuntington diseasemHTTnonhuman primatePET

Identifiers

PMID37591545
PMCPMC10586486

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.