Evidence map›Paper›PMID 37591233›Full record

ArticleJournal of speech, language, and hearing research : JSLHR2023

Profiling Number of Swallows per Bolus and Residue in Individuals With Amyotrophic Lateral Sclerosis.

Cara Donohue, Raele Robison, Catriona M Steele, James P Wymer, Emily K Plowman

Open access · greenAbstract read
In one paragraph

Article in Journal of speech, language, and hearing research : JSLHR, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Normal values for swallow events during endoscopic evaluation of swallowing: a preliminary study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Cara DonohueAerodigestive Research Core Laboratory, University of Florida, Gainesville.ORCID 0000-0002-5546-6081
Raele RobisonAerodigestive Research Core Laboratory, University of Florida, Gainesville.
Catriona M SteeleKITE Research Institute, University Health Network, Toronto, Ontario, Canada.ORCID 0000-0002-4294-6561
James P WymerDepartment of Neurology, University of Florida, Gainesville.
Emily K PlowmanAerodigestive Research Core Laboratory, University of Florida, Gainesville.ORCID 0000-0002-0198-4297
Google (United States) · US

Funding

Establishing Reference Values and Clinical Decision Points for Quantitative Videofluoroscopic Measures of SwallowingR01AG077481 · NIA · UNIVERSITY HEALTH NETWORK · PI Emily Kate Plowman, Catriona Margaret Steele · 2022 to 2026
$4.3M
Tongue-pressure timing for liquid flow detection and control in swallowingR01DC011020 · NIDCD · UNIVERSITY HEALTH NETWORK · PI STEELE, CATRIONA MARGARET · 2010 to 2020
$2.9M
Landis Outstanding Mentor Award SupplementR01NS100859 · NINDS · UNIVERSITY OF FLORIDA · PI PLOWMAN, EMILY KATE · 2017 to 2021
$2.0M
The Role of Homeostenosis in Bulbar Function in ALS and AgingK00AG076123 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI LOY, RAELE DONETHA · 2021 to 2024
$336k
NIA NIH HHS K00 AG076123NIA NIH HHS R01 AG077481NIDCD NIH HHS R01 DC011020NINDS NIH HHS R01 NS100859
6 · The paper itself

Abstract

purposeSwallowing efficiency impairments are the most prevalent and earliest manifestation of dysphagia in people with amyotrophic lateral sclerosis (pALS). We aimed to profile number of swallows elicited in pALS across thin liquid, moderately thick liquid, extremely thick liquid, and crackers compared to expected healthy reference data and to determine relationships between degree of pharyngeal residue, number of elicited swallows, and swallowing safety.

methodpALS underwent standardized videofluoroscopic swallowing studies of 10 bolus trials. Trained raters performed duplicate, independent, and blinded ratings to derive Dynamic Imaging Grade of Swallowing Toxicity (DIGEST) efficiency and safety grades and Analysis of Swallowing Physiology: Events, Kinematics, and Timing (ASPEKT) percent total pharyngeal residue. Number of swallows per bolus was quantified (1 = typical, 2 = atypically high, 3 = extremely high). Kruskal-Wallis, Pearson chi-square, and odds ratio analyses were performed at bolus and participant levels. KEY

resultsAt the bolus level ( CONCLUSION AND INFERENCES: pALS demonstrated a higher number of swallows per bolus compared to healthy reference data that may represent a compensation for reductions in swallowing efficiency to clear pharyngeal residue.

Indexed as

Amyotrophic Lateral SclerosisDeglutition DisordersDeglutitionFluoroscopyFoodHumansPharynx

Identifiers

PMID37591233
PMCPMC10713014
OpenAlexW4385910536

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.