ArticlePLoS neglected tropical diseases2023
Prevalence and associated factors of active trachoma among 1-9 years of age children in Andabet district, northwest Ethiopia, 2023: A multi-level mixed-effect analysis.
Article in PLoS neglected tropical diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 4 of them syntheses that pooled it.
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10 citing papers in PubMed, 4 syntheses or guidelines pooled it, 11 citations in OpenAlex.
- Predictors of trachoma among children aged 1-9 years in Ethiopia: a comprehensive systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Prevalence and associated factors of active trachoma among children of 1 to 9 years in low-income countries of Africa: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Pooled it
- Active trachoma among children aged 1-9 years in Ethiopia: A meta-analysis from 2019 to 2024.PloS one · 2025Pooled it
- Trachoma Prevalence and Associated WASH and Behavioral Risk Among Rural Communities of North Gondar Zone, Ethiopia: A Community-Based Cross-Sectional Study.Journal of tropical medicine · 2026Article
- Hygiene and sanitation-related socio-ecological contexts and constraints of communities in districts with persistent trachoma, Southern Ethiopia.BMC infectious diseases · 2025Article
- Prevalence and spatial distributions of trachomatous inflammation-follicular among children aged 1-9 years in rural areas of Yilmana Densa and Gonji Kolela districts, Northwestern Ethiopia.BMC public health · 2025Article
- Global, Regional, and National Burden of Trachoma: Cross-Country Inequalities, 1990-2021, with Projections to 2040.Ophthalmology and therapy · 2025Article
- Active trachoma and associated factors in children aged 1 to 9 years living in Sasiga rural districts, East Wallaga Zone, Ethiopia, in 2022: a community- based cross-sectional study.BMC ophthalmology · 2024Article
- Factors associated with trachoma in persistently endemic setting in Southern Ethiopia: a community-based cross-sectional study.The Pan African medical journal · 2024Article
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Authors and funding
12 authors at 5 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundTrachoma is the chief cause of preventable blindness worldwide and has been earmarked for elimination as a public health problem by 2030. Despite the five-year Surgery, Antibiotics, Facial cleanliness, and Environmental improvement (SAFE)-based interventions in the Andabet district, the prevalence of trachomatous follicular (TF) was 37%. With such a high prevalence of TF, the determinant factors were not revealed. Besides, there were no reports on the overall prevalence of active trachoma (i.e.TF and or trachomatous intense (TI)).
objectiveTo determine the prevalence and associated factors of active trachoma among 1-9 years of age children in the Andabet district.
methodA community-based cross-sectional study was conducted among children aged under nine years from March 1-30, 2023 in Andabet district, Northwest Ethiopia. Multi-stage systematic random sampling was employed to reach 540 children. A multilevel mixed-effect logistic regression analysis was employed to assess factors associated with active trachoma. We fitted both random effect and fixed effect analysis. Finally, variables with p<0.05 in the multivariable multilevel analysis were claimed to be significantly associated with active trachoma.
resultIn this study, the overall prevalence of active trachoma was 35.37% (95% CI: 31.32%, 39.41%). The prevalence of TF and TI was 31.3% and 4.07% respectively. In the multilevel logistic regression analysis ocular discharge, fly-eye contact, latrine utilization, and source of water were significantly associated with the prevalence of active trachoma.
conclusionIn this study, the prevalence of active trachoma was much higher than the World Health Organization (WHO) threshold prevalence. Ocular discharge, fly-eye contact, latrine utilization, and source of water were independent determinants of active trachoma among children (1-9 years). Therefore, paying special attention to these high-risk groups could decrease the prevalence of a neglected hyperendemic disease, active trachoma.
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