Evidence map›Paper›PMID 37590272›Full record

ArticlePLoS neglected tropical diseases2023

Burden and risk factors of snakebite in Mopeia, Mozambique: Leveraging larger malaria trials to generate data of this neglected tropical disease.

Emma O'Bryan, Saimado Imputiua, Eldo Elobolobo, Patricia Nicolas, Julia Montana, Edgar Jamisse, Humberto Munguambe, Aina Casellas, Paula Ruiz-Castillo, Regina Rabinovich and 3 more

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Emma O'BryanISGlobal, Barcelona Institute for Global Health, Barcelona, Spain.ORCID 0000-0002-0154-1816
Saimado ImputiuaCentro de Investigação em Saúde de Manhiça, Mopeia, Mozambique.
Eldo EloboloboCentro de Investigação em Saúde de Manhiça, Mopeia, Mozambique.
Patricia NicolasISGlobal, Barcelona Institute for Global Health, Barcelona, Spain.
Julia MontanaISGlobal, Barcelona Institute for Global Health, Barcelona, Spain.
Edgar JamisseCentro de Investigação em Saúde de Manhiça, Mopeia, Mozambique.
Humberto MunguambeCentro de Investigação em Saúde de Manhiça, Mopeia, Mozambique.
Aina CasellasISGlobal, Barcelona Institute for Global Health, Barcelona, Spain.
Paula Ruiz-CastilloISGlobal, Barcelona Institute for Global Health, Barcelona, Spain.
Regina RabinovichISGlobal, Barcelona Institute for Global Health, Barcelona, Spain.
Francisco SauteISGlobal, Barcelona Institute for Global Health, Barcelona, Spain.
Charfudin SacoorISGlobal, Barcelona Institute for Global Health, Barcelona, Spain.
Carlos ChaccourISGlobal, Barcelona Institute for Global Health, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSnakebite is a neglected disease that disproportionally affects the rural poor. There is a dearth of evidence regarding incidence and risk factors in snakebite-endemic countries. Without this basic data, it will be impossible to achieve the target of a 50% reduction of snakebite morbidity and mortality by 2030 as set by the World Health Organization.

methodsThis was a descriptive analysis nested in a 2021 community-based demographic survey of over 70,000 individuals conducted in Mopeia, Mozambique, in preparation for a cluster randomized trial to test an intervention for malaria. We describe the incidence rate, demographics, socioeconomic indicators and outcomes of snakebite in this population.

findingsWe found the incidence of self-reported snakebite in Mopeia to be 393 bites per 100,000 person-years at risk, with 2% of households affected in the preceding 12 months. Whilst no fatalities were recorded, over 3,000 days of work or school days were lost with an individual household economic impact higher than that of uncomplicated malaria. 1 in 6 of those affected did not fully recover at the time of the study. We found significant relationships between age older than 15, use of firewood for household fuel, and animal possession with snakebite.

conclusionsThis study exposes higher than expected incidence and burden of snakebite in rural Mozambique. Whilst snakebite elimination in Mozambique seems unattainable today, it remains a preventable disease with manageable sequelae. We have shown that snakebite research is particularly easy to nest in larger studies, making this a practical and cost-effective way of estimating its incidence.

Indexed as

MalariaSnake BitesAnimalsHumansMozambiqueNeglected DiseasesRisk Factors

Identifiers

PMID37590272
PMCPMC10464960

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.