Evidence map›Paper›PMID 37590260›Full record

ArticlePloS one2023

The association between all-cause mortality and HIV acquisition risk groups in the United States, 2001-2014.

Fatma M Shebl, Yiqi Qian, Julia H A Foote, Nattanicha Wattananimitgul, Krishna P Reddy, Anne M Neilan, Andrea L Ciaranello, Elena Losina, Kenneth A Freedberg, Emily P Hyle

Abstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Clinical Consequences of Delaying Implementation of Long-Acting Antiretroviral Therapy for People With HIV and Persistent Viremia in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fatma M SheblMedical Practice Evaluation Center, Massachusetts General Hospital, Boston, Massachusetts, Unite States of America.ORCID 0000-0002-9750-0049
Yiqi QianMedical Practice Evaluation Center, Massachusetts General Hospital, Boston, Massachusetts, Unite States of America.
Julia H A FooteMedical Practice Evaluation Center, Massachusetts General Hospital, Boston, Massachusetts, Unite States of America.
Nattanicha WattananimitgulMedical Practice Evaluation Center, Massachusetts General Hospital, Boston, Massachusetts, Unite States of America.
Krishna P ReddyMedical Practice Evaluation Center, Massachusetts General Hospital, Boston, Massachusetts, Unite States of America.
Anne M NeilanMedical Practice Evaluation Center, Massachusetts General Hospital, Boston, Massachusetts, Unite States of America.
Andrea L CiaranelloMedical Practice Evaluation Center, Massachusetts General Hospital, Boston, Massachusetts, Unite States of America.
Elena LosinaHarvard University Center for AIDS Research (CFAR), Cambridge, Massachusetts, United States of America.
Kenneth A FreedbergMedical Practice Evaluation Center, Massachusetts General Hospital, Boston, Massachusetts, Unite States of America.
Emily P HyleMedical Practice Evaluation Center, Massachusetts General Hospital, Boston, Massachusetts, Unite States of America.ORCID 0000-0001-8721-106X

Funding

Development and application of a new simulation model for COVID-19R01AI042006 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Kenneth Alan Freedberg, Anne Neilan · 1998 to 2026
$12.9M
Novel Methods to Inform HIV/TB Clinical Trial DevelopmentR01AI093269 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI REDDY, KRISHNA P · 2011 to 2024
$6.8M
The Impact of Hearing Loss Treatment Scale-Up in Persons Aging with HIV on Dementia Risk, Quality of Life, and Healthcare CostsR01AG069575 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI HYLE, EMILY PARKER · 2021 to 2025
$4.6M
Diagnosing and preventing HIV infection in adolescents and young adults in the US: clinical impact and cost-effectivenessK08HD094638 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI NEILAN, ANNE · 2018 to 2023
$936k
Cardiovascular Disease in South African HIV Patients: Value of PreventionK01HL123349 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI HYLE, EMILY PARKER · 2016 to 2020
$896k
NHLBI NIH HHS K01 HL123349NIAID NIH HHS R01 AI042006NIAID NIH HHS R01 AI093269NIA NIH HHS R01 AG069575NICHD NIH HHS K08 HD094638
6 · The paper itself

Abstract

objectiveTo investigate associations between all-cause mortality and human immunodeficiency virus (HIV) acquisition risk groups among people without HIV in the United States.

methodsWe used data from 23,657 (NHANES) participants (2001-2014) and the Linked Mortality File to classify individuals without known HIV into HIV acquisition risk groups: people who ever injected drugs (ever-PWID); men who have sex with men (MSM); heterosexually active people at increased risk for HIV (HIH), using low income as a proxy for increased risk. We used Cox proportional hazards models to estimate adjusted and unadjusted all-cause mortality hazard ratios (HR) with 95% confidence intervals (CI).

resultsCompared with sex-specific heterosexually active people at average risk for HIV (HAH), the adjusted HR (95% CI) were: male ever-PWID 1.67 (1.14, 2.46), female ever-PWID 3.50 (2.04, 6.01), MSM 1.51 (1.00, 2.27), male HIH 1.68 (1.04, 2.06), female HIH 2.35 (1.87, 2.95), and male ever-PWID 1.67 (1.14, 2.46).

conclusionsMost people at increased risk for HIV in the US experience higher all-cause mortality than people at average risk. Strategies addressing social determinants that increase HIV risk should be incorporated into HIV prevention and other health promotion programs.

Indexed as

HIV InfectionsSexual and Gender MinoritiesSubstance Abuse, IntravenousFemaleHIVHomosexuality, MaleHumansMaleNutrition SurveysUnited States

Identifiers

PMID37590260
PMCPMC10434931

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.