ArticlePloS one2023
The impact of COVID-19 on maternal death and fetal death, a cohort study in Brazil.
Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 30 citations in OpenAlex.
- Changes in Placentas of Pregnant Women Infected with COVID-19.International journal of molecular sciences · 2025Article
- Maternal mortality in Egypt during the COVID-19 pandemic using record-based data from January 2020 to December 2021.Scientific reports · 2025Article
- Pregnancy reduces COVID-19 vaccine immunity against novel variants.NPJ vaccines · 2025Article
- Reply to matters arising: Safety of SARS-CoV-2 vaccination during pregnancy - obstetric outcomes from a large cohort study: methodological biases in study design with potential impact on the study's interpretation.BMC pregnancy and childbirth · 2025Article
- Impact of the COVID-19 pandemic on small vulnerable newborns: an interrupted time series analysis in Peru and Brazil.Journal of global health · 2025Article
- Health system financing fragmentation and maternal mortality transition in Mexico, 2000-2022.International journal for equity in health · 2025Article
- Space-time trends in fetal mortality in Brazil, 1996-2021.Revista de saude publica · 2025Article
- Clinical characteristic and outcomes of pregnant women with COVID-19: The PROUDEST prospective cohort study.PloS one · 2025Article
- Fetal mortality before and during the COVID-19 pandemic: a single-center cohort study in Rio de Janeiro, Brazil.Revista da Associacao Medica Brasileira (1992) · 2025Article
- Article
- Analysis of the influence of the COVID-19 pandemic on maternal mortality trends, 2011-2021.Revista latino-americana de enfermagem · 2025Article
- Add-on hemoperfusion in SARS-CoV-2-infected pregnant patients: a case series.Journal of medical case reports · 2024Article
- A particular epidemiological profile: disparities in access to contraceptive methods in Brazil during the SARS-CoV-2 (COVID-19) pandemic.Scientific reports · 2024Article
- Hospitalizations for coronavirus disease 2019: an analysis of the occurrence waves.Scientific reports · 2024Article
- SARS-CoV-2 infection during pregnancy and the risk of adverse maternal outcomes in the Republic of Georgia: a national birth registry-based cohort study.BMC pregnancy and childbirth · 2024Article
- Influence of sociodemographic and obstetric factors on maternal mortality in Brazil from 2011 to 2021.BMC women's health · 2024Article
- Article
- Association between chronic health conditions and severe acute respiratory syndrome in pregnant women: an exploratory study.Revista da Escola de Enfermagem da U S P · 2024Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe study aimed to evaluate the risk of maternal death and fetal death among pregnant women infected with SARS-CoV-2.
methodsThis is a retrospective cohort study among pregnant women with secondary data from the National Live Births System (Sistema Nacional de Nascidos Vivos), National Mortality System (Sistema Nacional de Mortalidade), and e-SUS Health Surveillance System (Sistema e-SUS Vigilância em Saúde). Pregnant women confirmed for COVID-19 had positive RT-PCR between March 2020 and May 2021, pregnant women without COVID-19 were those without notification for disease. Maternal death, fetal death, and stillbirth were assessed as primary outcomes.
resultsWe included 68,673 pregnant women not notified as suspected of COVID-19 and 1,386 with a confirmed diagnosis of COVID-19. Among pregnant women with COVID-19, 1013 (73.0%) were aged 20 to 34 years, 655 (47.2%) were brown, 907 (65.4%) had ≥ 8 years of education, in the third trimester of pregnancy (41.5%), undergoing cesarean section (64.5%). In adjusted analyses, COVID-19 in pregnancy had a higher risk of maternal death (relative risk [RR] 18.73-95% confidence interval [95%CI] 11.07-31.69), fetal death/stillbirth (RR 1.96-95%CI 1.18-3.25), preterm birth [RR 1.18-95%CI 1.01-1.39], cesarean delivery (RR 1.07-95%CI 1.02-1.11), and cesarean delivery occurring before the onset of labor (RR 1.33-95%CI 1.23-1.44).
conclusionCOVID-19 may contribute to unfavorable pregnancy outcomes. Results showed that pregnant women infected with SARS-CoV-2 had a higher risk of maternal death, fetal death/stillbirth, preterm birth, cesarean delivery, and cesarean section occurring before the onset of labor.
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