Evidence map›Paper›PMID 37589939›Full record

ArticleAnalytical and bioanalytical chemistry2023

A strategy to enhance SERS detection sensitivity through the use of SiO

Jiadong Chen, Qian Yu, Mengdan Lu, Chang Su Jeon, Sung Hyun Pyun, Jaebum Choo

Abstract read
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In one paragraph

Article in Analytical and bioanalytical chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jiadong ChenDepartment of Chemistry, Chung-Ang University, Seoul, 06974, South Korea.
Qian YuDepartment of Chemistry, Chung-Ang University, Seoul, 06974, South Korea.
Mengdan LuDepartment of Chemistry, Chung-Ang University, Seoul, 06974, South Korea.
Chang Su JeonR&D Center, Speclipse Inc., Seongnam, 13461, South Korea.
Sung Hyun PyunR&D Center, Speclipse Inc., Seongnam, 13461, South Korea. ceo@speclipse.com.
Jaebum ChooDepartment of Chemistry, Chung-Ang University, Seoul, 06974, South Korea. jbchoo@cau.ac.kr.

Funding

Chung-Ang University Young Scientist Scholarship (CAYSS) CAYSS-2021National Research Foundation of Korea 2020R1A5A1018052
6 · The paper itself

Abstract

The development of rapid and accurate assays is crucial to prevent the rapid spread of highly contagious respiratory infections such as coronavirus (COVID-19). Here, we developed a surface-enhanced Raman scattering (SERS)-enzyme-linked immunosorbent assay (ELISA) method that allows for the screening of multiple patient samples with high sensitivity on a 1536-well plate. As the well number on the ELISA well plate increases from 96 to 1536, the throughput of the assay increases but the sensitivity decreases due to the low number of biomarkers and the increase in non-specific binding species. To address this problem, silica (SiO

Indexed as

COVID-19SARS-CoV-2Silicon DioxideSpectrum Analysis, RamanCoronavirus Nucleocapsid ProteinsEnzyme-Linked Immunosorbent AssayGoldHumansImmunoassayLimit of DetectionMetal NanoparticlesPhosphoproteinsCoronavirus Nucleocapsid ProteinsGoldnucleocapsid phosphoprotein, SARS-CoV-2PhosphoproteinsSilicon DioxideSARS-CoV-2SERS immunoassaySiO2 beadSurface-enhanced Raman scattering (SERS)Surface-to-volume ratio

Identifiers

PMID37589939

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.