Evidence map›Paper›PMID 37589927›Full record

SynthesisSleep & breathing = Schlaf & Atmung2024

Diurnal variation in variables related to cognitive performance: a systematic review.

Madhavi Munnilari, Tulasiram Bommasamudram, Judy Easow, David Tod, Evdokia Varamenti, Ben J Edwards, Aishwarya Ravindrakumar, Chloe Gallagher, Samuel A Pullinger

3 registry-linked trialsAbstract readSystematic Review
In one paragraph

Synthesis in Sleep & breathing = Schlaf & Atmung, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07466628 phase4completednot on this map

Effects of Caffeine Ingestion on Morning Cognitive and Muscle Strength Measures in Males, Where a Standardized Approach Has Been Employed

TypeinterventionalSponsorLiverpool John Moores UniversityRan2024 to 2025Enrolled15ConditionsCaffine, Placebo - Control, No PillArms300mg of of caffeine anhydrous in 3 capsules similar to PLACEBO in size and weight, Placebo, No Pill
NCT07466732 early_phase1enrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Effects of Caffeine Ingestion on Morning Cognitive and Muscle Repeated Sprint Performance in Males. Where a Standardized Approach Has Been Employed

TypeinterventionalSponsorLiverpool John Moores UniversityRan2025 to 2026Enrolled15ConditionsCaffeine, Placebo - Control, No PillArmsCaffeine, Placabo, No Pill
NCT07469852 phase1 / phase2active not recruitingnot on this mapstarted 2026, after this paper: background citation

Effects of Caffeine Ingestion on Morning Cognitive and 4-km Time Trial Performance in Males. Where a Standardized Approach Has Been Employed

TypeinterventionalSponsorLiverpool John Moores UniversityRan2026 to 2026Enrolled15ConditionsCaffeine, Placebo - Control, No PillArmsCaffeine (300 mg), Placebo, No Pill
3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Madhavi MunnilariDepartment of Exercise and Sports Science, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.ORCID 0000-0002-7796-302X
Tulasiram BommasamudramDepartment of Exercise and Sports Science, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India. tulasiram.b@manipal.edu.ORCID 0000-0002-8077-7359
Judy EasowDepartment of Exercise and Sports Science, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.ORCID 0000-0003-2979-0520
David TodFaculty of Health & Medicine, Lancaster University, Lancaster, UK.ORCID 0000-0003-1084-6686
Evdokia VaramentiSports Science Department, Aspire Academy, Doha, Qatar.ORCID 0000-0002-7375-9419
Ben J EdwardsResearch Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK.ORCID 0000-0001-8913-0941
Aishwarya RavindrakumarDepartment of Exercise and Sports Science, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.ORCID 0000-0003-4093-1291
Chloe GallagherResearch Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK.ORCID 0000-0002-0712-4482
Samuel A PullingerSport Science Department, Inspire Institute of Sport, Vidyanagar, Dist, Bellary, 583275, India. samuel.pullinger@inspireinstituteofsport.com.ORCID 0000-0001-7680-3991

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this review was to assess current evidence regarding changes in cognitive function according to time-of-day (TOD) and assess the key components of research design related to manuscripts of chronobiological nature.

methodsAn English-language literature search revealed 523 articles through primary database searches, and 1868 via organization searches/citation searching. The inclusion criteria were met by eleven articles which were included in the review. The inclusion criteria set were healthy adult males, a minimum of two timepoints including morning and evening, cognitive measures of performance, and peer-reviewed academic paper.

resultsIt was established that cognitive performance varies with TOD and the degree of difference is highly dependent on the type of cognitive task with differences ranging from 9.0 to 34.2% for reaction time, 7.3% for alertness, and 7.8 to 40.3% for attention. The type of cognitive function was a determining factor as to whether the performance was better in the morning, evening, or afternoon.

conclusionAlthough some studies did not establish TOD differences, reaction time and levels of accuracy were highest in the evening. This implies that cognitive processes are complex, and existing research is contradictory. Some studies or cognitive variables did not show any measurable TOD effects, which may be due to differences in methodology, subjects involved, testing protocols, and confounding factors. No studies met all requirements related to chronobiological research, highlighting the issues around methodology. Therefore, future research must use a rigorous, approach, minimizing confounding factors that are specific to examinations of TOD.

Indexed as

Circadian RhythmCognitionAdultAttentionHumansMaleReaction TimeCircadian rhythmsCognitive performanceDiurnal variationReviewROBROBINS-ITime-of-day

Identifiers

PMID37589927
PMCPMC10955027

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.