Evidence map›Paper›PMID 37589896›Full record

Trial reportEuropean journal of nutrition2023

Dietary intake of preformed vitamin A and provitamin A carotenoids are not associated with serum retinol and carotenoid concentrations among children 36-59 months of age in rural Burkina Faso: a cross-sectional study.

Olivier O Sombié, Augustin N Zeba, Jérome W Somé, Adama Kazienga, Jeoffray Diendere, Jean F Bationo, Christopher Davis, Michael Grahn, Sherry Tanumihardjo, Stefaan De Henauw and 1 more

Abstract readClinical Trial
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In one paragraph

Trial report in European journal of nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Olivier O SombiéUnité Nutrition et Maladies Métaboliques, Institut de Recherche en Sciences de la Santé/Direction Régionale de l'Ouest, Bobo Dioulasso, Burkina Faso. sombieolivier@yahoo.fr.ORCID http://orcid.org/0000-0002-7985-6893
Augustin N ZebaUnité Nutrition et Maladies Métaboliques, Institut de Recherche en Sciences de la Santé/Direction Régionale de l'Ouest, Bobo Dioulasso, Burkina Faso.
Jérome W SoméUnité Nutrition et Maladies Métaboliques, Institut de Recherche en Sciences de la Santé, Ouagadougou, Burkina Faso.
Adama KaziengaDepartment of Translational Physiology, Infectiology and Public Health, Faculty of Veterinary Medicine, Ghent University, Ghent, Belgium.
Jeoffray DiendereUnité Nutrition et Maladies Métaboliques, Institut de Recherche en Sciences de la Santé/Direction Régionale de l'Ouest, Bobo Dioulasso, Burkina Faso.
Jean F BationoAfrican Union Development Agency-New Partnership for Africa's Development, Midrand, South Africa.
Christopher DavisDepartment of Nutritional Sciences, University of Wisconsin-Madison, Madison, USA.
Michael GrahnDepartment of Nutritional Sciences, University of Wisconsin-Madison, Madison, USA.
Sherry TanumihardjoDepartment of Nutritional Sciences, University of Wisconsin-Madison, Madison, USA.
Stefaan De HenauwPublic Health Nutrition Unit, Department of Public Health and Primary Care, Faculty of Health Sciences, Ghent University, 9000, Ghent, Belgium.
Souheila AbbeddouPublic Health Nutrition Unit, Department of Public Health and Primary Care, Faculty of Health Sciences, Ghent University, 9000, Ghent, Belgium.

Funding

International Atomic Energy Agency RAF 6047
6 · The paper itself

Abstract

purposeThis study aimed to assess the association between dietary intake of preformed vitamin A (VA) and pro-VA carotenoids and serum retinol and carotenoid concentrations among 36-59-month-old children in a rural area in Burkina Faso.

methodsTwo community-based cross-sectional studies were conducted in a rural area of Burkina Faso and included 115 children aged 36-59 months. Dietary intake of preformed VA and pro-VA was assessed directly by 24-h dietary recall. Serum retinol and carotenoid (α- and β-carotene, and β-cryptoxanthin) concentrations were measured. The associations between serum retinol and carotenoid concentrations and their respective dietary intake were assessed by multiple linear regression.

resultsGeometric mean [95% CI] adjusted serum retinol concentration in children was 0.86 [0.81; 0.92] µmol/L. The prevalence of low adjusted serum retinol concentration (< 0.7 µmol/L) was 26.8%. Geometric mean [95% CI] serum carotenoid concentrations were: α-carotene (0.03 [0.02; 0.03] µmol/L), β-carotene (0.14 [0.12; 0.16] µmol/L), and β-cryptoxanthin (0.17 [0.15; 0.21] µmol/L). Dietary intakes of α- and β-carotene and adjusted serum retinol and α-carotene concentrations were significantly higher during the rainy season. In multiple linear regressions, no associations were found between dietary intakes of preformed VA and pro-VA carotenoids and serum retinol and carotenoid concentrations in children aged 36-59 months in Burkina Faso. There was no effect of season on the associations between preformed VA and pro-VA carotenoids intake and serum retinol and carotenoid concentrations.

conclusionsThis study shows that dietary intakes of preformed VA and pro-VA carotenoids based on 24-h dietary recall method cannot be used as proxy of serum retinol and carotenoid concentrations in this population.

trial registrationThe study was registered retrospectively (22 March 2018) as a clinical trial with the Pan African Clinical Trials Registry (Cochrane South Africa; PACTR201803002999356).

Indexed as

beta CaroteneVitamin ABeta-CryptoxanthinBurkina FasoCarotenoidsChildChild, PreschoolCross-Sectional StudiesEatingHumansProvitaminsRetrospective Studiesalpha-carotenebeta CaroteneBeta-CryptoxanthinCarotenoidsProvitaminsVitamin ABurkina FasoCarotenoidsChildrenDietary intakeRetinolVitamin A

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.