Evidence map›Paper›PMID 37589460›Full record

ArticlemSphere2023

Intracellular replication of

Abby R Kroken, Keith A Klein, Patrick S Mitchell, Vincent Nieto, Eric J Jedel, David J Evans, Suzanne M J Fleiszig

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Infection and immunity · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. ThemBio · 2025
    Article
  8. Urinary tract infections and catheter-associated urinary tract infections caused byMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  9. Article
  10. The Role ofPharmaceutics · 2024
    Review
  11. Article
  12. Evidence for intracellularJournal of bacteriology · 2024
    Review
  13. Secreted Metabolites fromMicroorganisms · 2024
    Article
  14. The L-lactate dehydrogenases ofbioRxiv : the preprint server for biology · 2024
    Article
  15. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Abby R KrokenDepartment of Microbiology and Immunology, Loyola University Chicago , Maywood, Illinois, USA.ORCID 0000-0003-1807-1125
Keith A KleinDepartment of Microbiology and Immunology, Loyola University Chicago , Maywood, Illinois, USA.
Patrick S MitchellDepartment of Microbiology, University of Washington , Seattle, Washington, USA.
Vincent NietoHerbert Wertheim School of Optometry & Vision Science, University of California , Berkeley, California, USA.
Eric J JedelHerbert Wertheim School of Optometry & Vision Science, University of California , Berkeley, California, USA.
David J EvansHerbert Wertheim School of Optometry & Vision Science, University of California , Berkeley, California, USA.
Suzanne M J FleiszigHerbert Wertheim School of Optometry & Vision Science, University of California , Berkeley, California, USA.
University of California, Berkeley · USLoyola University Chicago · USTouro University California · USUniversity of Washington · US

Funding

Translational Research Center to Expedite Novel Therapies in Cystic FibrosisP30DK089507 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI PRADEEP k SINGH · 2010 to 2026
$21.4M
SIGNIFICANCE OF CORNEAL CELL INVASION BY BACTERIAR01EY011221 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI Suzanne MJ FLEISZIG · 1995 to 2026
$8.4M
Translation of evolution-guided insights for new models of human infectious diseaseDP2AI154432 · NIAID · UNIVERSITY OF WASHINGTON · PI MITCHELL, PATRICK S · 2021 to 2025
$2.5M
Inflammasome-mediated corneal epithelial cell defenses inhibited by pathogenic bacteriaR01EY034239 · NEI · LOYOLA UNIVERSITY CHICAGO · PI Abby R Kroken · 2022 to 2026
$1.9M
Mechanisms for bacterial dissemination in corneal infectionF32EY029152 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI NIETO, VINCENT · 2018 to 2020
$179k
Corneal infection: bacterial localization versus virulenceF32EY025969 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI KROKEN, ABBY R · 2015 to 2017
$173k
NEI NIH HHS F32 EY025969NEI NIH HHS F32 EY029152NEI NIH HHS R01 EY011221NEI NIH HHS R01 EY034239NIAID NIH HHS DP2 AI154432NIDDK NIH HHS P30 DK089507
6 · The paper itself

Abstract

Pathogenesis of

Indexed as

InflammasomesPseudomonas aeruginosaEpithelial CellsHeLa CellsHumansVacuolesInflammasomescaspase-4corneaepitheliuminflammasomekeratitisPseudomonas aeruginosapyroptosistype three secretion system

Identifiers

PMID37589460
PMCPMC10597407
OpenAlexW4385897719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.