Evidence map›Paper›PMID 37588670›Full record

ArticleFrontiers in neurology2023

Clinical heterogeneity of neuro-inflammatory PET profiles in early Alzheimer's disease.

Dominique Gouilly, Anne-Sophie Salabert, Elsa Bertrand, Marie Goubeaud, Hélène Catala, Johanne Germain, Nadéra Ainaoui, Marie Rafiq, Marie Benaiteau, Jasmine Carlier and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Dominique GouillyToulouse Neuroimaging Center, UMR 1214, Inserm/UPS, Toulouse, France.
Anne-Sophie SalabertToulouse Neuroimaging Center, UMR 1214, Inserm/UPS, Toulouse, France.
Elsa BertrandCenter of Clinical Investigation (CIC 1436), Toulouse Purpan University Hospital Center, Toulouse, France.
Marie GoubeaudCenter of Clinical Investigation (CIC 1436), Toulouse Purpan University Hospital Center, Toulouse, France.
Hélène CatalaCenter of Clinical Investigation (CIC 1436), Toulouse Purpan University Hospital Center, Toulouse, France.
Johanne GermainCenter of Clinical Investigation (CIC 1436), Toulouse Purpan University Hospital Center, Toulouse, France.
Nadéra AinaouiCenter of Clinical Investigation (CIC 1436), Toulouse Purpan University Hospital Center, Toulouse, France.
Marie RafiqToulouse Neuroimaging Center, UMR 1214, Inserm/UPS, Toulouse, France.
Marie BenaiteauDepartment of Cognitive Neurology, Epilepsy and Movement Disorders, Toulouse Purpan University Hospital Center, Toulouse, France.
Jasmine CarlierDepartment of Cognitive Neurology, Epilepsy and Movement Disorders, Toulouse Purpan University Hospital Center, Toulouse, France.
Leonor NogueiraLaboratory of Cell Biology and Cytology, Toulouse Purpan University Hospital Center, Toulouse, France.
Mélanie PlantonToulouse Neuroimaging Center, UMR 1214, Inserm/UPS, Toulouse, France.
Anne HitzelDepartment of Nuclear Medicine, Toulouse Purpan University Hospital Center, Toulouse, France.
Déborah MéligneToulouse Neuroimaging Center, UMR 1214, Inserm/UPS, Toulouse, France.
Benjamine SartonToulouse Neuroimaging Center, UMR 1214, Inserm/UPS, Toulouse, France.
Stein SilvaToulouse Neuroimaging Center, UMR 1214, Inserm/UPS, Toulouse, France.
Béatrice LemesleDepartment of Cognitive Neurology, Epilepsy and Movement Disorders, Toulouse Purpan University Hospital Center, Toulouse, France.
Pierre PayouxToulouse Neuroimaging Center, UMR 1214, Inserm/UPS, Toulouse, France.
Claire ThalamasCenter of Clinical Investigation (CIC 1436), Toulouse Purpan University Hospital Center, Toulouse, France.
Patrice PéranToulouse Neuroimaging Center, UMR 1214, Inserm/UPS, Toulouse, France.
Jérémie ParienteToulouse Neuroimaging Center, UMR 1214, Inserm/UPS, Toulouse, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The relationship between neuroinflammation and cognition remains uncertain in early Alzheimer's disease (AD). We performed a cross-sectional study to assess how neuroinflammation is related to cognition using TSPO PET imaging and a multi-domain neuropsychological assessment. A standard uptake value ratio (SUVR) analysis was performed to measure [

Indexed as

AlzheimerneuroinflammationneuropsychologyPET scanTSPO

Identifiers

PMID37588670
PMCPMC10425281

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.