Evidence map›Paper›PMID 37588574›Full record

ArticleBJA open2022

Evaluation of the Analgesia Nociception Index and videopupillometry to predict post-tonsillectomy morphine requirements in children

Bruno Evrard, Cyrielle Lefebvre, Paul Spiry, Charles Hodler, Catherine Chapellas, Baher Youssef, François Gauthier, Loïc Marais, Anaïs Labrunie, Marie Douchez and 3 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BJA open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03698565 (Evaluation of the Analgesia Nociception Index and Videopupillometry to Predict a Child's Post-tonsillectomy Morphine Prescription), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03698565 nacompletednot on this map

Evaluation of the Analgesia Nociception Index and Videopupillometry to Predict a Child's Post-tonsillectomy Morphine Prescription

TypeinterventionalSponsorUniversity Hospital, LimogesRan2018 to 2020Enrolled93ConditionsPain, PostoperativeArmsNerve stimulation of the ulnar nerve
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Bruno EvrardMedical-surgical ICU, Dupuytren Teaching Hospital, Limoges, France.
Cyrielle LefebvreDepartment of Anaesthesiology and Intensive Care, Dupuytren Teaching Hospital, Limoges, France.
Paul SpiryDepartment of Anaesthesiology and Intensive Care, Dupuytren Teaching Hospital, Limoges, France.
Charles HodlerDepartment of Anaesthesiology and Intensive Care, Dupuytren Teaching Hospital, Limoges, France.
Catherine ChapellasDepartment of Anaesthesiology and Intensive Care, Dupuytren Teaching Hospital, Limoges, France.
Baher YoussefDepartment of Anaesthesiology and Intensive Care, Dupuytren Teaching Hospital, Limoges, France.
François GauthierDepartment of Anaesthesiology and Intensive Care, Dupuytren Teaching Hospital, Limoges, France.
Loïc MaraisResearch and Innovation Department, Dupuytren Teaching Hospital, Limoges, France.
Anaïs LabrunieDepartment of Epidemiology, Biostatistics and Research Methodology, Dupuytren Teaching Hospital, Limoges, France.
Marie DouchezDepartment of Anaesthesiology and Intensive Care, Dupuytren Teaching Hospital, Limoges, France.
Patrick SengesDepartment of Anaesthesiology and Intensive Care, Dupuytren Teaching Hospital, Limoges, France.
Jérôme CrosDepartment of Anaesthesiology and Intensive Care, Dupuytren Teaching Hospital, Limoges, France.
Nathalie Nathan-DenizotDepartment of Anaesthesiology and Intensive Care, Dupuytren Teaching Hospital, Limoges, France.
Hôpital Dupuytren · FRInserm · FRUniversité de Limoges · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Tonsil surgery causes significant and challenging postoperative pain. The Analgesia Nociception Index (ANI) and videopupillometry are two techniques of interest to monitor nociception in adults and may predict postoperative morphine requirements. We hypothesised that these techniques could predict the need for morphine after tonsillectomy in children. The main objective was to assess the prognostic significance of ANI and videopupillometry, measured at the end of surgery, on morphine consumption determined by a Face, Legs, Activity, Cry, Consolability (FLACC) scale score >3 in the Post Anesthesia Care Unit (PACU). Methods: A single-centre, prospective, interventional study evaluating children between 2 and 7 yr old undergoing tonsil surgery was performed. ANI and videopupillometry with tetanic stimulation were measured under general anaesthesia 4 min after the end of the surgical procedure. Each child was evaluated every 10 min by a nurse using the FLACC scale in the PACU and blinded to the measurements performed in the operating theatre. Results: Eighty-nine children were analysed and 39 (44%) received morphine in the PACU. Neither ANI values nor videopupillometry values were predictive of postoperative morphine consumption (areas under the receiver operating characteristic curve 0.54, 95% confidence interval [CI; 0.42-0.65], and Conclusions: Neither ANI nor videopupillometry performed at the end of surgery can predict morphine consumption in the PACU in children undergoing tonsillectomy.

Indexed as

analgesiaAnalgesia Nociception IndexFLACC scalepaediatric anaesthesiatonsillectomyvideopupillometry

Identifiers

PMID37588574
PMCPMC10430817
OpenAlexW4288987517

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.