Evidence map›Paper›PMID 37588481›Full record

ArticleDigital biomarkers

Automated Real-World Video Analysis of Sit-to-Stand Transitions Predicts Parkinson's Disease Severity.

Catherine Morgan, Alessandro Masullo, Majid Mirmehdi, Hanna Kristiina Isotalus, Ferdian Jovan, Ryan McConville, Emma L Tonkin, Alan Whone, Ian Craddock

Open access · goldAbstract read
In one paragraph

Article in Digital biomarkers. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Video-Based Data-Driven Models for Diagnosing Movement Disorders: Review and Future Directions.Movement disorders : official journal of the Movement Disorder Society · 2025
    Review
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Catherine MorganTranslational Health Sciences, University of Bristol, Bristol, UK.
Alessandro MasulloFaculty of Engineering, University of Bristol, Digital Health Offices, 1 Cathedral Square, Bristol, UK.
Majid MirmehdiFaculty of Engineering, University of Bristol, Digital Health Offices, 1 Cathedral Square, Bristol, UK.
Hanna Kristiina IsotalusFaculty of Engineering, University of Bristol, Digital Health Offices, 1 Cathedral Square, Bristol, UK.
Ferdian JovanFaculty of Engineering, University of Bristol, Digital Health Offices, 1 Cathedral Square, Bristol, UK.
Ryan McConvilleFaculty of Engineering, University of Bristol, Digital Health Offices, 1 Cathedral Square, Bristol, UK.
Emma L TonkinFaculty of Engineering, University of Bristol, Digital Health Offices, 1 Cathedral Square, Bristol, UK.
Alan WhoneTranslational Health Sciences, University of Bristol, Bristol, UK.
Ian CraddockFaculty of Engineering, University of Bristol, Digital Health Offices, 1 Cathedral Square, Bristol, UK.
University of Bristol · GBNorth Bristol NHS Trust · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Introduction: Technology holds the potential to track disease progression and response to neuroprotective therapies in Parkinson's disease (PD). The sit-to-stand (STS) transition is a frequently occurring event which is important to people with PD. The aim of this study was to demonstrate an automatic approach to quantify STS duration and speed using a real-world free-living dataset and look at clinical correlations of the outcomes, including whether STS parameters change when someone withholds PD medications. Methods: Eighty-five hours of video data were collected from 24 participants staying in pairs for 5-day periods in a naturalistic setting. Skeleton joints were extracted from the video data; the head trajectory was estimated and used to estimate the STS parameters of duration and speed. Results: 3.14 STS transitions were seen per hour per person on average. Significant correlations were seen between automatic and manual STS duration (Pearson rho - 0.419, Conclusion: We demonstrate a novel approach to automatically quantify and ecologically validate two STS parameters which correlate with gold-standard clinical tools measuring disease severity in PD.

Indexed as

Home environmentInfluence and/or predict health-related outcomesMobilityObjective dataParkinson’s disease-related motor symptomsVideo recording

Identifiers

PMID37588481
PMCPMC10425718
OpenAlexW4385802895

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.