Evidence map›Paper›PMID 37588135›Full record

ArticleFrontiers in bioengineering and biotechnology2023

Novel patch biomaterial treatment for colon diverticulosis in swine model.

Xiaomei Guo, Bhavesh Patel, Ling Han, William G Van Alstine, Jillian N Noblet, Sean D Chambers, Ghassan S Kassab

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaomei GuoCalifornia Medical Innovations Institute Inc, San Diego, CA, United States.
Bhavesh PatelCalifornia Medical Innovations Institute Inc, San Diego, CA, United States.
Ling HanCalifornia Medical Innovations Institute Inc, San Diego, CA, United States.
William G Van AlstineCook Research Incorporated, West Lafayette, IN, United States.
Jillian N NobletCook Medical, Bloomington, IN, United States.
Sean D ChambersCook Medical, Bloomington, IN, United States.
Ghassan S KassabCalifornia Medical Innovations Institute Inc, San Diego, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current leading managements for diverticular disease cannot prevent the recurrence of diverticulitis, bleeding and/or other complications. There is an immediate need for developing new minimal invasive therapeutic strategies to prevent and treat this disease. Through a biomechanical analysis of porcine colon with diverticular lesions, we proposed a novel adhesive patch concept aiming at mechanical reconstruction of the diseased colon wall. This study aims to evaluate the surgical feasibility (safety and efficacy) of pulmonary visceral pleura (PVP) patch therapy using a pig model of diverticulosis. Six female Yucatan miniature pigs underwent collagenase injection (CI) for the development of diverticular lesions. The lesions in each animal either received patch implantation (treated group,

Indexed as

colon diverticulapig modelPVP patchsafetytreatment

Identifiers

PMID37588135
PMCPMC10425590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.