Evidence map›Paper›PMID 37588049›Full record

ArticleFrontiers in nutrition2023

Kombucha tea as an anti-hyperglycemic agent in humans with diabetes - a randomized controlled pilot investigation.

Chagai Mendelson, Sabrina Sparkes, Daniel J Merenstein, Chloe Christensen, Varun Sharma, Sameer Desale, Jennifer M Auchtung, Car Reen Kok, Heather E Hallen-Adams, Robert Hutkins

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04107207 (Pilot Study to Evaluate Effects of Kombucha as a Hyperglycemic Therapeutic Agent Within Diabetic Human Subjects), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04107207 nacompletednot on this map

Pilot Study to Evaluate Effects of Kombucha as a Hyperglycemic Therapeutic Agent Within Diabetic Human Subjects

TypeinterventionalSponsorGeorgetown UniversityRan2019 to 2020Enrolled12ConditionsDiabetes MellitusArmsGinger Kombucha, Ginger Water
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 42 citations in OpenAlex.

  1. Trial
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  10. Comparing the Effects ofClinical diabetes : a publication of the American Diabetes Association · 2025
    Article
  11. Review
  12. Article
  13. Network Pharmacology and Molecular Docking Approach to Identify and Investigate the Mechanisms of Active Components of Areca Catechu in Relation to Gut Disorders.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2025
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  18. Metabolomics andHeliyon · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Chagai MendelsonDepartment of Medicine, MedStar Georgetown University Hospital, Washington, DC, United States.
Sabrina SparkesDepartment of Human Science, Georgetown University School of Health, Washington, DC, United States.
Daniel J MerensteinDepartment of Human Science, Georgetown University School of Health, Washington, DC, United States.
Chloe ChristensenDepartment of Food Science and Technology, University of Nebraska, Lincoln, NE, United States.
Varun SharmaDivision of General Internal Medicine, MedStar Georgetown University Hospital, Washington, DC, United States.
Sameer DesaleMedStar Health, Washington, DC, United States.
Jennifer M AuchtungDepartment of Food Science and Technology, University of Nebraska, Lincoln, NE, United States.
Car Reen KokDepartment of Food Science and Technology, University of Nebraska, Lincoln, NE, United States.
Heather E Hallen-AdamsDepartment of Food Science and Technology, University of Nebraska, Lincoln, NE, United States.
Robert HutkinsDepartment of Food Science and Technology, University of Nebraska, Lincoln, NE, United States.
University of Nebraska–Lincoln · USGeorgetown University · USGeorgetown University Medical Center · USMedStar Georgetown University Hospital · USMedStar Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Kombucha is a popular fermented tea that has attracted considerable attention due, in part, to its suggested health benefits. Previous results from animal models led us to hypothesize kombucha may reduce blood sugar levels in humans with diabetes. The objective of this pilot clinical study was to evaluate kombucha for its anti-hyperglycemic activities in adults with diabetes mellitus type II. Methods: The study was organized as a prospective randomized double-blinded crossover study at a single-center urban hospital system. Participants ( Results: Kombucha lowered average fasting blood glucose levels at 4 weeks compared to baseline (164 vs. 116 mg/dL, Discussion: Although this pilot study was limited by a small sample size, kombucha was associated with reduced blood glucose levels in humans with diabetes. Larger follow-up studies are warranted. Clinical trial registration: ClinicalTrials.gov, identifier NCT04107207.

Indexed as

clinical trialdiabetes mellitushuman subjectskombuchamicroorganisms

Identifiers

PMID37588049
PMCPMC10426908
OpenAlexW4385458789

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.