Evidence map›Paper›PMID 37587907›Full record

ArticleOccupational medicine (Oxford, England)2023

First-trimester occupational exposures and hypertensive disorders of pregnancy among US nurses.

I Agarwal, S Wang, J Stuart, S Strohmaier, E Schernhammer, J Rich-Edwards, J H Kang

Open access · greenAbstract read
In one paragraph

Article in Occupational medicine (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

I AgarwalMaine Health Institute for Research, Maine Medical Center, Scarborough 04074, MN, USA.ORCID 0000-0002-6979-5660
S WangDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.ORCID 0000-0002-5605-2016
J StuartDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
S StrohmaierDepartment of Epidemiology, Center for Public Health, Medical University of Vienna, Vienna 1090, Austria.ORCID 0000-0002-9387-2056
E SchernhammerDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
J Rich-EdwardsDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
J H KangChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
Brigham and Women's Hospital · USHarvard University · USMaine Medical Center · USMedical University of Vienna · AT

Funding

Life Course Cancer Epidemiology Cohort in WomenU01CA176726 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI ELIASSEN, A. HEATHER, WILLETT, WALTER C. · 2018 to 2025
$22.4M
Female-Specific Risk Factors for CVD: The Impact of Adverse Pregnancy Outcomes on Subsequent Mental Health and CVD RiskK01HL159281 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI STUART, JENNIFER JACQUELINE · 2022 to 2024
$348k
NCI NIH HHS U01 CA176726NHLBI NIH HHS K01 HL159281
6 · The paper itself

Abstract

backgroundLimited and conflicting data exist regarding the impact of first-trimester nursing occupational exposures on hypertensive disorders of pregnancy (HDP).

aimsTo investigate whether first-trimester night shift work, work hours and work-related activities are associated with HDP.

methodsWe conducted a cross-sectional analysis of 6610 women within the Nurses' Health Study II. We used multiple logistic regression to estimate the odds ratios (ORs) and 95% confidence intervals (CIs) for the relation of occupational exposures to HDP.

resultsNine per cent of respondents reported an HDP in the index pregnancy (gestational hypertension: n = 354, 5%, preeclampsia: n = 222, 3%). First-trimester fixed or rotating night shift work was not significantly associated with gestational hypertension or preeclampsia compared to day shift work only. Compared to those working 21-40 h/week, working overtime (≥41 h/week) was not associated with gestational hypertension but was associated with 43% higher odds of preeclampsia (95% CI 1.02, 2.00). For part-time work (≤20 h/week), the OR was 0.76 (95% CI 0.56, 1.02) for gestational hypertension and 0.64 (95% CI 0.43, 0.97) for preeclampsia. The odds of preeclampsia were 3% higher per additional hour worked per week (95% CI 1.01-1.04). Compared to 0-4 h spent standing or walking per day, standing or walking ≥9 h daily was associated with 32% lower odds of gestational hypertension (95% CI 0.47, 0.99) but was not significantly associated with preeclampsia. Frequency of heavy lifting was not associated with either hypertensive disorder or pregnancy.

conclusionsAmong nurses, working overtime was associated with higher odds of preeclampsia.

Indexed as

Hypertension, Pregnancy-InducedOccupational ExposurePre-EclampsiaCross-Sectional StudiesFemaleHumansPregnancyPregnancy Trimester, First

Identifiers

PMID37587907
PMCPMC11009503
OpenAlexW4385897728

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.