Evidence map›Paper›PMID 37587869›Full record

ArticleArthritis care & research2024

Diagnostic Accuracy Study of the Pediatric-Specific Ultrasound Scoring System for the Knee Joint in Children With Juvenile Idiopathic Arthritis.

Patricia Vega-Fernandez, Kelly Rogers, Alyssa Sproles, Sherry Thornton, Jennifer Huggins, Daniel J Lovell, Amy Cassedy, Arthur B Meyers, Tracy V Ting

Open access · bronzeAbstract read
In one paragraph

Article in Arthritis care & research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Sonographic and Disease Activity Findings Related With Medication Change in JIA: A Historical Cohort Study.Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Patricia Vega-FernandezUniversity of Cincinnati and Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.ORCID 0000-0002-4911-7256
Kelly RogersUniversity of Cincinnati and Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Alyssa SprolesUniversity of Cincinnati and Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Sherry ThorntonUniversity of Cincinnati and Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Jennifer HugginsUniversity of Cincinnati and Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Daniel J LovellUniversity of Cincinnati and Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.ORCID 0000-0003-1604-0130
Amy CassedyUniversity of Cincinnati and Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Arthur B MeyersUniversity of Cincinnati and Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.ORCID 0000-0002-5785-0861
Tracy V TingUniversity of Cincinnati and Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Cincinnati Children's Hospital Medical Center · US

Funding

LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., KISSELA, BRETT M · 2015 to 2024
$37.5M
Tissue Repository CoreP30AR070549 · NIAMS · CINCINNATI CHILDRENS HOSP MED CTR · PI Leah Claire Kottyan · 2016 to 2026
$7.7M
KL2 Training ProgramKL2TR001426 · NCATS · UNIVERSITY OF CINCINNATI · PI ZELLER, MARGARET H · 2015 to 2024
$6.8M
Pediatric musculOskeletal & RheumaTology Innovation COre center (PORTICO)P30AR076316 · NIAMS · CINCINNATI CHILDRENS HOSP MED CTR · PI BRUNNER, HERMINE I · 2019 to 2023
$3.4M
NCATS NIH HHS KL2 TR001426NCATS NIH HHS UL1 TR001425NIAMS NIH HHS P30 AR070549NIAMS NIH HHS P30 AR076316
6 · The paper itself

Abstract

objectiveWe undertook this study to validate the Pediatric Arthritis Ultrasound Scoring System for the knee joint (PAUSS-knee) in children with juvenile idiopathic arthritis (JIA).

methodsChildren with JIA were enrolled to prospectively receive a musculoskeletal ultrasound (MSUS) examination of the knee and a physical examination to determine presence/absence of clinical arthritis. MSUS images were scored using the PAUSS-knee, a semiquantitative MSUS scoring system (0-3, normal to severe) for B-mode and power Doppler mode. In addition to MSUS, a subset of participants also received magnetic resonance imaging (MRI) of the knee, which was scored according to the combined Juvenile Arthritis MRI Scoring (JAMRIS) system. Spearman's correlations (r

resultsEighty children with JIA contributed 112 MSUSs and 25 MRIs of the knee. Of the knees, 41% (n = 46) had clinical evidence of arthritis. The B-mode PAUSS-knee score moderately correlated with clinically determined arthritis (r

conclusionOur data indicate that the PAUSS-knee has excellent accuracy for the diagnosis of arthritis when compared with MRI. The PAUSS-knee has the potential to effectively inform JIA medical decision-making in real time.

Indexed as

Arthritis, JuvenileBiomarkersChildHumansKnee JointMagnetic Resonance ImagingUltrasonographyBiomarkers

Identifiers

PMID37587869
PMCPMC10841426
OpenAlexW4385898818

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.