Evidence map›Paper›PMID 37587826›Full record

ReviewCurrent molecular medicine2025

The Emerging Role of LncRNA AWPPH in Multiple Cancers: A Review Study.

Mohsen Sheykhhasan, Fateme Dermani, Nematollah Gheibi, Ishwaree Datta, Hamid Sadeghi, Saeideh Gholamzadeh Khoei

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current molecular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Genetic/epigenetic RNA dysregulation in type 2Frontiers in endocrinology · 2025
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Mohsen SheykhhasanMedical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.ORCID 0000-0001-8599-7492
Fateme DermaniDepartment of Biological Sciences, Florida State University, Florida, USA.
Nematollah GheibiCellular and Molecular Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran.
Ishwaree DattaDepartment of Biological Sciences, Florida State University, Florida, USA.
Hamid SadeghiMedical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
Saeideh Gholamzadeh KhoeiMedical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.ORCID 0000-0003-2675-9392
Florida State University · USQazvin University of Medical Sciences · IR

Funding

Deputy of Research and Technology, Qazvin University of Medical Sciences, Qazvin, Iran 400000502
6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) are transcribed RNA molecules longer than 200 nucleotides in length that have no protein-coding potential. They are able to react with DNA, RNA, and protein. Hence they involve in regulating gene expression at the epigenetic, transcriptional, post-transcriptional, and translational levels. LncRNAs have been proven to play an important role in human malignancies and prognostic outcomes. In this review, we will comprehensively and functionally discuss the role of a novel identified lncRNA, namely lncRNA WAPPH located on human chromosome 2q13, in various cancers. Increasing research studies have shown that lncRNA AWPPH is deregulated in different malignancies, including breast cancer, gastric cancer, colorectal cancer, ovarian cancer, bladder cancer, leukemia, and others. LncRNA WAPPH serves as an oncogene in tumorigenesis and the development of cancer. Moreover, lncRNA AWPPH is involved in numerous biological processes of solid and blood cancers. Taken together, based on our scrutiny analysis, lncRNA AWPPH can be regarded as a putative biomarker for diagnosis or therapeutic target in human malignancies.

Indexed as

Gene Expression Regulation, NeoplasticNeoplasmsRNA, Long NoncodingAnimalsBiomarkers, TumorHumansBiomarkers, TumorRNA, Long NoncodingAWPPHCancer biomarkerdiagnosislong non-coding RNAneoplasm.therapeutic

Identifiers

PMID37587826
OpenAlexW4385897348

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.