Evidence map›Paper›PMID 37587776›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

Parahydrogen-Polarized [1-

Luca Nagel, Martin Gierse, Wolfgang Gottwald, Zumrud Ahmadova, Martin Grashei, Pascal Wolff, Felix Josten, Senay Karaali, Christoph A Müller, Sebastian Lucas and 14 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Multi-Vendor and Multi-Site Characterization ofMagnetic resonance in medicine · 2026
    Article
  3. Hyperpolarization of PyridineAngewandte Chemie (International ed. in English) · 2026
    Article
  4. Exploring Limits of [1-Small science · 2026
    Article
  5. Article
  6. Biocompatible SABRE Hyperpolarization of [1-Chemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  7. Article
  8. Article
  9. Detection of the Carcinogen Benzo[Analytical chemistry · 2026
    Article
  10. Article
  11. Ultra-low fieldCommunications chemistry · 2026
    Article
  12. Review
  13. Review
  14. Article
  15. Multidimensional pH-Temperature Mapping of SABRE-SHEATHThe journal of physical chemistry. B · 2025
    Article
  16. The journal of physical chemistry. B · 2025
    Article
  17. BiologicalSmall science · 2025
    Article
  18. Article
  19. SABRE Ir-IMes Catalysis for the Masses.Molecules (Basel, Switzerland) · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Luca NagelDepartment of Nuclear Medicine, TUM School of Medicine, Klinikum rechts der Isar of Technical University of Munich, 81675, Munich, Germany.ORCID 0000-0002-5530-6264
Martin GierseNVision Imaging Technologies GmbH, 89081, Ulm, Germany.
Wolfgang GottwaldDepartment of Nuclear Medicine, TUM School of Medicine, Klinikum rechts der Isar of Technical University of Munich, 81675, Munich, Germany.
Zumrud AhmadovaNVision Imaging Technologies GmbH, 89081, Ulm, Germany.
Martin GrasheiDepartment of Nuclear Medicine, TUM School of Medicine, Klinikum rechts der Isar of Technical University of Munich, 81675, Munich, Germany.ORCID 0000-0002-5019-9359
Pascal WolffNVision Imaging Technologies GmbH, 89081, Ulm, Germany.
Felix JostenNVision Imaging Technologies GmbH, 89081, Ulm, Germany.
Senay KaraaliNVision Imaging Technologies GmbH, 89081, Ulm, Germany.
Christoph A MüllerNVision Imaging Technologies GmbH, 89081, Ulm, Germany.
Sebastian LucasNVision Imaging Technologies GmbH, 89081, Ulm, Germany.
Jochen ScheuerNVision Imaging Technologies GmbH, 89081, Ulm, Germany.
Christoph MüllerNVision Imaging Technologies GmbH, 89081, Ulm, Germany.
John BlanchardNVision Imaging Technologies GmbH, 89081, Ulm, Germany.
Geoffrey J ToppingDepartment of Nuclear Medicine, TUM School of Medicine, Klinikum rechts der Isar of Technical University of Munich, 81675, Munich, Germany.
Andre WendlingerDepartment of Nuclear Medicine, TUM School of Medicine, Klinikum rechts der Isar of Technical University of Munich, 81675, Munich, Germany.
Nadine SetzerDepartment of Nuclear Medicine, TUM School of Medicine, Klinikum rechts der Isar of Technical University of Munich, 81675, Munich, Germany.
Sandra SühnelDepartment of Nuclear Medicine, TUM School of Medicine, Klinikum rechts der Isar of Technical University of Munich, 81675, Munich, Germany.
Jonas HandwerkerNVision Imaging Technologies GmbH, 89081, Ulm, Germany.
Christophoros VassiliouNVision Imaging Technologies GmbH, 89081, Ulm, Germany.
Frits H A van HeijsterDepartment of Nuclear Medicine, TUM School of Medicine, Klinikum rechts der Isar of Technical University of Munich, 81675, Munich, Germany.
Stephan KnechtNVision Imaging Technologies GmbH, 89081, Ulm, Germany.
Michael KeimNVision Imaging Technologies GmbH, 89081, Ulm, Germany.
Franz SchillingDepartment of Nuclear Medicine, TUM School of Medicine, Klinikum rechts der Isar of Technical University of Munich, 81675, Munich, Germany.ORCID 0000-0001-5239-4628
Ilai SchwartzNVision Imaging Technologies GmbH, 89081, Ulm, Germany.

Funding

Bundesministerium für Bildung und Forschung 13N16450Deutsche Forschungsgemeinschaft 391523415
6 · The paper itself

Abstract

Hyperpolarization techniques increase nuclear spin polarization by more than four orders of magnitude, enabling metabolic MRI. Even though hyperpolarization has shown clear value in clinical studies, the complexity, cost and slowness of current equipment limits its widespread use. Here, a polarization procedure of [1-

Indexed as

HydrogenPyruvic AcidAnimalsCarbon IsotopesHydrogenationMagnetic Resonance ImagingCarbon IsotopesHydrogenPyruvic Acidhyperpolarizationmagnetic resonance imaging (MRI)metabolic imagingparahydrogenpyruvate

Identifiers

PMID37587776
PMCPMC10602543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.