Evidence map›Paper›PMID 37587366›Full record

ArticleWorld journal of urology2023

Pulsed thulium:YAG laser-ready to dust all urinary stone composition types? Results from a PEARLS analysis.

Jia-Lun Kwok, Eugenio Ventimiglia, Vincent De Coninck, Mariela Corrales, Alba Sierra, Frédéric Panthier, Felipe Pauchard, Florian Schmid, Manuela Hunziker, Cédric Poyet and 4 more

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in World journal of urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06721975 (Prospective Single-center Study Comparing Thulium Fiber Laser to Pulsed Thulium), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06721975 narecruitingnot on this mapstarted 2024, after this paper: background citation

Prospective Single-center Study Comparing Thulium Fiber Laser to Pulsed Thulium:YAG Laser in the Ureteroscopic Treatment of Nephrolithiasis

TypeinterventionalSponsorUniversity of California, San DiegoRan2024 to 2026Enrolled50ConditionsKidney Stones, NephrolithiasisArmsThulio pulsed Thulium:YAG (p-Tm:YAG), Thulium Laser Fiber (TFL)
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  10. [Stones in the lower pole and their treatment].Urologie (Heidelberg, Germany) · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 8 countries.

Jia-Lun KwokDepartment of Urology, University Hospital Zurich, University of Zurich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-9758-6225
Eugenio VentimigliaProgressive Endourological Association for Research and Leading Solutions (PEARLS), Paris, France.ORCID http://orcid.org/0000-0003-3654-1629
Vincent De ConinckProgressive Endourological Association for Research and Leading Solutions (PEARLS), Paris, France.ORCID http://orcid.org/0000-0002-4983-5055
Mariela CorralesProgressive Endourological Association for Research and Leading Solutions (PEARLS), Paris, France.ORCID http://orcid.org/0000-0002-1461-8464
Alba SierraProgressive Endourological Association for Research and Leading Solutions (PEARLS), Paris, France.ORCID http://orcid.org/0000-0003-2474-8067
Frédéric PanthierProgressive Endourological Association for Research and Leading Solutions (PEARLS), Paris, France.ORCID http://orcid.org/0000-0003-3055-2984
Felipe PauchardProgressive Endourological Association for Research and Leading Solutions (PEARLS), Paris, France.ORCID http://orcid.org/0000-0003-2295-0042
Florian SchmidDepartment of Urology, University Hospital Zurich, University of Zurich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-0862-5027
Manuela HunzikerDepartment of Urology, University Hospital Zurich, University of Zurich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland.
Cédric PoyetDepartment of Urology, University Hospital Zurich, University of Zurich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-3648-6941
Michel DaudonCRISTAL Laboratory, Hôpital Tenon, Sorbonne Université, Paris, France.
Olivier TraxerProgressive Endourological Association for Research and Leading Solutions (PEARLS), Paris, France.ORCID http://orcid.org/0000-0002-2459-3803
Daniel EberliDepartment of Urology, University Hospital Zurich, University of Zurich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland.ORCID http://orcid.org/0000-0001-8866-8010
Etienne Xavier KellerDepartment of Urology, University Hospital Zurich, University of Zurich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland. etiennexavier.keller@usz.ch.ORCID http://orcid.org/0000-0003-1667-7609
University of Zurich · CHEuropean Association of Urology · NLSorbonne Université · FRHospital Naval Almirante Nef · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate whether stone dust can be obtained from all prevailing stone composition types using the novel pulsed thulium:YAG (p-Tm:YAG), including analysis of stone particle size after lithotripsy.

methodsHuman urinary stones of 7 different compositions were subjected to in vitro lithotripsy using a p-Tm:YAG laser with 270 µm silica core fibers (Thulio

resultsThe p-Tm:YAG laser was able to produce stone dust from lithotripsy up to measured smallest mesh size of 63 µm in all seven stone composition types. Notably, all dust samples from all seven stone types and with all three laser settings had high counts of particles in the size range agreeing with the definition stone dust, i.e., ≤ 250 µm.

conclusionThis is the first study in the literature proving the p-Tm:YAG laser capable of dusting all prevailing human urinary stone compositions, with production of dust particles ≤ 250 µm. These findings are pivotal for the broader future implementation of the p-Tm:YAG in clinical routine.

Indexed as

Lasers, Solid-StateLithotripsy, LaserUrinary CalculiDustHumansThuliumDustThuliumEndourologyKidney stonesLaserPulsed thulium:YAGStone dustUreteroscopy

Identifiers

PMID37587366
PMCPMC10581948
OpenAlexW4385857838

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.