ArticleNature2023
Mapping the T cell repertoire to a complex gut bacterial community.
Open access · greenAbstract read
In one paragraph
Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
11.5field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 71 citations in OpenAlex.
- Antigen-specific activation of gut immune cells drives autoimmune neuroinflammation.Gut microbes · 2026Article
- Soil-derived microbiota induces T regulatory cells and protect against mouse colitis, metabolic disease, and sepsis.Gut microbes · 2026Article
- The gut microbiome in graft-versus-host disease: mechanisms of immune modulation and therapeutic approaches.Gut microbes · 2026Review
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- Gut commensal bifidobacteria are associated with restrained inflammatory reprogramming in human monocyte-derived dendritic cells.iScience · 2026Article
- Colorectal cancers with distinct metastatic potential trigger divergent early T cell responses.bioRxiv : the preprint server for biology · 2026Article
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- Article
- Spatial transcriptomics maps host-gut microbiome biogeography at high resolution.Nature microbiology · 2026Article
- Tissue-specific clonal selection and differentiation of CD4⁺ T cells during infection.Nature immunology · 2026Article
- Strain-level antigen variation facilitates immune evasion in Bacteroides thetaiotaomicron.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- Identification and characterization of dietary antigens in oral tolerance.Science immunology · 2026Article
- Differential effects of two common GVHD prophylaxis regimens on the gut microbiome: Results from the BMT CTN 1801 study.bioRxiv : the preprint server for biology · 2026Article
- De novo identification of the specificities of recurrently identified human T cell receptors.Science advances · 2026Article
- Striking a balance: how the gut microbiome shapes the fate of intestinal CD4+ T cells.Discovery immunology · 2026Review
- Design and application of synthetic human gut microbial communities.Gut microbes · 2025Review
- Gut microbiota gate host exposure to cholinesterase inhibitors from dietary Solanums.bioRxiv : the preprint server for biology · 2025Article
- Microbiome-derived bile acid signatures in early life and their association with islet autoimmunity.Nature communications · 2025Article
- Microbiota interaction with Tregs: a target for colitis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025Review
- Antigen-presenting cells as arbiters of mucosal tolerance and immunity.Nature immunology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 6 institutions in 1 country.
Kazuki NagashimaDepartment of Bioengineering, Stanford University, Stanford, CA, USA.ORCID 0000-0002-8593-136X
Aishan ZhaoDepartment of Bioengineering, Stanford University, Stanford, CA, USA.
Katayoon AtabakhshDepartment of Bioengineering, Stanford University, Stanford, CA, USA.
Minwoo BaeDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.ORCID 0000-0002-0313-5520
Jamie E BlumDepartment of Chemical Engineering, Stanford University, Stanford, CA, USA.
Allison WeakleyChEM-H Institute, Stanford University, Stanford, CA, USA.
Sunit JainChEM-H Institute, Stanford University, Stanford, CA, USA.ORCID 0000-0002-5888-3702
Xiandong MengChEM-H Institute, Stanford University, Stanford, CA, USA.
Alice G ChengDepartment of Gastroenterology, Stanford School of Medicine, Stanford, CA, USA.
Min WangDepartment of Bioengineering, Stanford University, Stanford, CA, USA.
Steven HigginbottomDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford University, Stanford, CA, USA.
Alex DimasDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford University, Stanford, CA, USA.
Pallavi MurugkarChEM-H Institute, Stanford University, Stanford, CA, USA.
Elizabeth S SattelyDepartment of Chemical Engineering, Stanford University, Stanford, CA, USA.ORCID 0000-0002-7352-859X
James J MoonCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0001-8246-931X
Emily P BalskusDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.ORCID 0000-0001-5985-5714
Michael A FischbachDepartment of Bioengineering, Stanford University, Stanford, CA, USA. fischbach@fischbachgroup.org.ORCID 0000-0003-3079-8247
Stanford University · USChan Zuckerberg Initiative (United States) · USHoward Hughes Medical Institute · USHarvard University · USCardiovascular Institute of the South · USStanford Medicine · US
Funding
T cell Tolerance to Enteric Commensal BacteriaR01DK126910 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI MOON, JAMES J · 2021 to 2024
$2.0MIdentification and characterization of natural products from the human microbiotaR01DK110174 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FISCHBACH, MICHAEL ANDREW · 2016 to 2019
$1.4MDecode and design T cell induction by a complex gut microbial communityR00AI173524 · NIAID · HARVARD UNIVERSITY · PI Kazuki Nagashima · 2025 to 2026
$498kDecode and design T cell induction by a complex gut microbial communityK99AI173524 · NIAID · STANFORD UNIVERSITY · PI NAGASHIMA, KAZUKI · 2023 to 2024
$261kNIAID NIH HHS K99 AI173524NIAID NIH HHS R00 AI173524NIDDK NIH HHS R01 DK110174NIDDK NIH HHS R01 DK126910
Abstract
Certain bacterial strains from the microbiome induce a potent, antigen-specific T cell response
Indexed as
BacteriaGastrointestinal MicrobiomeT-LymphocytesAnimalsAntigens, SurfaceBacillotaCell SeparationGerm-Free LifeHybridomasMiceReceptors, Antigen, T-CellSymbiosisTh17 CellsT-Lymphocytes, RegulatoryAntigens, SurfaceReceptors, Antigen, T-Cell
Identifiers
What OpenQuestion holds
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.