Evidence map›Paper›PMID 37587313›Full record

ArticleAnalytical and bioanalytical chemistry2023

Detection of botanical adulterants in saffron powder.

Jana Ryparova Kvirencova, Klara Navratilova, Vojtech Hrbek, Jana Hajslova

Abstract read
In one paragraph

Article in Analytical and bioanalytical chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Separative Techniques Coupled to Mass Spectrometry for Metabolomic Analysis.Advances in experimental medicine and biology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jana Ryparova KvirencovaDepartment of Food Analysis and Nutrition, University of Chemistry and Technology Prague (UCT Prague), Technicka 3, 166 28, Prague 8, Czech Republic.
Klara NavratilovaDepartment of Food Analysis and Nutrition, University of Chemistry and Technology Prague (UCT Prague), Technicka 3, 166 28, Prague 8, Czech Republic.
Vojtech HrbekDepartment of Food Analysis and Nutrition, University of Chemistry and Technology Prague (UCT Prague), Technicka 3, 166 28, Prague 8, Czech Republic.
Jana HajslovaDepartment of Food Analysis and Nutrition, University of Chemistry and Technology Prague (UCT Prague), Technicka 3, 166 28, Prague 8, Czech Republic. jana.hajslova@vscht.cz.

Funding

Metrofood-CZ MEYS Grants - number LN2023064Metrofood-CZ MEYS Grants - numbers LM2018100Vysoká Škola Chemicko-technologická v Praze A1_FPBT_2021_001Vysoká Škola Chemicko-technologická v Praze A1_FPBT_2022_005Vysoká Škola Chemicko-technologická v Praze A1_FPBT_2023_002Vysoká Škola Chemicko-technologická v Praze A2_FPBT_2021_052
6 · The paper itself

Abstract

Saffron is a unique spice obtained by drying stigmas of saffron flowers (Crocus sativus L.). Due to its high price, economically motivated adulteration occurs relatively often. The presented study aimed to develop an effective strategy for the detection of the following potential botanical adulterants used for a saffron substitution or dilution: safflower (Carthamus tinctorius L.), calendula (Calendula officinalis L.), turmeric (Curcuma longa L.), achiote (Bixa orellana L.), red pepper (Capsicum spp.), mountain arnica (Arnica montana L.), beet (Beta vulgaris L.), and pomegranate (Punica granatum L.). A non-target screening strategy based on ultra-high performance reverse-phase liquid chromatography coupled to tandem high-resolution mass spectrometry (UHPLC-HRMS/MS) was employed for the analysis of an aqueous ethanol plant extract. By using multivariate statistical methods, principal components analysis (PCA), and partial least squares discriminant analysis (PLS-DA), for processing the generated "chemical fingerprints," metabolites unique to the investigated plants could be identified. To enable routine saffron authenticity control by target screening, an internal spectral database was developed; currently, it involves 82 unique markers. In this way, the detection addition as low as 1% (w/w) of all analyzed botanical adulterants in admixture with saffron was possible. The developed method was used to control 7 saffron powder samples from the Czech market, and none of the monitored adulterants were confirmed.

Indexed as

Beta vulgarisBiological ProductsCapsicumCrocusAntioxidantsColoring AgentsPowdersSpicesAntioxidantsBiological ProductsColoring AgentsPowdersAuthenticityBotanical adulterantsCrocus sativus L.Metabolomic fingerprintingSaffronUHPLC-HRMS/MS

Identifiers

PMID37587313
PMCPMC10474180

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.