Evidence map›Paper›PMID 37587131›Full record

ArticleNPJ microgravity2023

Biofilm formation of Pseudomonas aeruginosa in spaceflight is minimized on lubricant impregnated surfaces.

Pamela Flores, Samantha A McBride, Jonathan M Galazka, Kripa K Varanasi, Luis Zea

Abstract read
In one paragraph

Article in NPJ microgravity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Biofilms: from the cradle of life to life support.NPJ biofilms and microbiomes · 2026
    Review
  4. Storage stability ofFrontiers in microbiology · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. ReducedMicroorganisms · 2024
    Article
  10. Article
  11. Morphology ofLife (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pamela FloresBioServe Space Technologies, Aerospace Engineering Sciences Department, University of Colorado Boulder, Boulder, CO, 80309, USA. pamela.flores@colorado.edu.ORCID http://orcid.org/0000-0003-4878-9429
Samantha A McBrideMassachusetts Institute of Technology (MIT), Cambridge, MA, 02139, USA.ORCID http://orcid.org/0000-0002-6402-1359
Jonathan M GalazkaSpace Biosciences Division, NASA Ames Research Center, Moffett Field, CA, 94035, USA.ORCID http://orcid.org/0000-0002-4153-0249
Kripa K VaranasiMassachusetts Institute of Technology (MIT), Cambridge, MA, 02139, USA. varanasi@mit.edu.
Luis ZeaBioServe Space Technologies, Aerospace Engineering Sciences Department, University of Colorado Boulder, Boulder, CO, 80309, USA. luis.zea@colorado.edu.ORCID http://orcid.org/0000-0002-4301-9620

Funding

National Aeronautics and Space Administration (NASA) 80NSSC17K0036National Aeronautics and Space Administration (NASA) 80NSSC21K1950
6 · The paper itself

Abstract

The undesirable, yet inevitable, presence of bacterial biofilms in spacecraft poses a risk to the proper functioning of systems and to astronauts' health. To mitigate the risks that arise from them, it is important to understand biofilms' behavior in microgravity. As part of the Space Biofilms project, biofilms of Pseudomonas aeruginosa were grown in spaceflight over material surfaces. Stainless Steel 316 (SS316) and passivated SS316 were tested for their relevance as spaceflight hardware components, while a lubricant impregnated surface (LIS) was tested as potential biofilm control strategy. The morphology and gene expression of biofilms were characterized. Biofilms in microgravity are less robust than on Earth. LIS strongly inhibits biofilm formation compared to SS. Furthermore, this effect is even greater in spaceflight than on Earth, making LIS a promising option for spacecraft use. Transcriptomic profiles for the different conditions are presented, and potential mechanisms of biofilm reduction on LIS are discussed.

Identifiers

PMID37587131
PMCPMC10432549

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.