Evidence map›Paper›PMID 37587112›Full record

ArticleNature communications2023

Integrin β

Yaping Zhang, Xiaojuan Zhao, Bo Shen, Yanyan Bai, Claire Chang, Aleksandra Stojanovic, Can Wang, Andrew Mack, Gary Deng, Randal A Skidgel and 2 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. GRespiratory research · 2024
    Review
  6. Thromboinflammation and the Role of Platelets.Arteriosclerosis, thrombosis, and vascular biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Yaping Zhang *Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago, Chicago, IL, 60612, USA.ORCID http://orcid.org/0000-0003-0205-8807
Xiaojuan Zhao *Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago, Chicago, IL, 60612, USA.
Bo Shen *Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago, Chicago, IL, 60612, USA.ORCID http://orcid.org/0000-0002-5237-6144
Yanyan BaiDepartment of Pharmacology and Regenerative Medicine, University of Illinois at Chicago, Chicago, IL, 60612, USA.ORCID http://orcid.org/0000-0002-8365-8451
Claire ChangDepartment of Pharmacology and Regenerative Medicine, University of Illinois at Chicago, Chicago, IL, 60612, USA.
Aleksandra StojanovicDepartment of Pharmacology and Regenerative Medicine, University of Illinois at Chicago, Chicago, IL, 60612, USA.
Can WangDepartment of Pharmacology and Regenerative Medicine, University of Illinois at Chicago, Chicago, IL, 60612, USA.ORCID http://orcid.org/0000-0002-2665-0269
Andrew MackDepartment of Pharmacology and Regenerative Medicine, University of Illinois at Chicago, Chicago, IL, 60612, USA.ORCID http://orcid.org/0009-0000-7224-7537
Gary DengEli Lilly, Indianapolis, IN, 46285, USA.
Randal A SkidgelDupage Medical Technology, Inc., Chicago, IL, 60612, USA.
Ni ChengDepartment of Pharmacology and Regenerative Medicine, University of Illinois at Chicago, Chicago, IL, 60612, USA.ORCID http://orcid.org/0000-0002-9013-690X
Xiaoping DuDepartment of Pharmacology and Regenerative Medicine, University of Illinois at Chicago, Chicago, IL, 60612, USA. xdu@uic.edu.ORCID http://orcid.org/0000-0001-9842-8192
University of Illinois Chicago · USDuPage Medical Group · USEli Lilly (United States) · US

Funding

Mechanisms of integrin signaling and a new anti-platelet/anti-inflammatory approachR35HL150797 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Xiaoping Du · 2020 to 2026
$6.8M
Outside-in signaling mechanisms of platelet integrin alpha-llb-beta3R01HL080264 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DU, XIAOPING · 2007 to 2019
$4.6M
New Strategies for Treating Septic Vasculopathy Inflammation and ThrombosisR01HL125356 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BONINI, MARCELO G., DU, XIAOPING · 2014 to 2018
$3.4M
Developing a new drug for treating myocardial ischemia/reperfusion injuryR44HL156560 · NHLBI · DUPAGE MEDICAL TECHNOLOGY, INC. · PI SKIDGEL, RANDAL A · 2021 to 2022
$2.0M
Targeting integrin outside-in signaling for treating sepsisR44HL142396 · NHLBI · DUPAGE MEDICAL TECHNOLOGY, INC. · PI SKIDGEL, RANDAL A · 2021 to 2023
$2.0M
NHLBI NIH HHS R01 HL080264NHLBI NIH HHS R01 HL125356NHLBI NIH HHS R35 HL150797NHLBI NIH HHS R44 HL142396NHLBI NIH HHS R44 HL156560
6 · The paper itself

Abstract

The integrins and G protein-coupled receptors are both fundamental in cell biology. The cross talk between these two, however, is unclear. Here we show that β

Indexed as

GTP-Binding ProteinsSignal TransductionAnimalsExocytosisIntegrin beta3MiceRho Guanine Nucleotide Exchange FactorsGTP-Binding ProteinsIntegrin beta3Rho Guanine Nucleotide Exchange Factors

Identifiers

PMID37587112
PMCPMC10432399
OpenAlexW4385878004

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.