Evidence map›Paper›PMID 37587066›Full record

ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2023

Effect of mycophenolate mofetil alleviates carbon tetrachloride-induced liver fibrosis in mice.

Peng Ding, Pengpeng Zhang, Hao Li, Yingzi Ming

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Peng DingOrgan Transplantation Center, Third Xiangya Hospital, Central South University, Changsha 410013. 491825729@qq.com.
Pengpeng ZhangOrgan Transplantation Center, Third Xiangya Hospital, Central South University, Changsha 410013. zpp_china@163.com.
Hao LiOrgan Transplantation Center, Third Xiangya Hospital, Central South University, Changsha 410013.
Yingzi MingOrgan Transplantation Center, Third Xiangya Hospital, Central South University, Changsha 410013. myz_china@aliyun.com.
Central South University · CN

Funding

the National Natural Science Foundation 81771722 and 82100695the Natural Science Foundation of Hunan Province 2022JJ40759
6 · The paper itself

Abstract

objectivesHepatic fibrosis is a serious pathological consequence of chronic liver disease. Mycophenolate mofetil (MMF) is a commonly used immunosuppressant after organ transplant. However, the relationship between MMF and hepatic fibrosis remains unclear. This study aims to explore the effect of MMF on hepatic fibrosis in mice and the potential mechanism.

methodsA total of 24 mice (male, 8-week old, C57BL/6) were randomly divided into a control group, a MMF group, a carbon tetrachloride (CCl

resultsCompared with the CCl

conclusionsMMF could reduce CCl

Indexed as

Carbon TetrachlorideMycophenolic AcidAnimalsLiver CirrhosisMaleMiceMice, Inbred C57BLRNA, MessengerTransforming Growth Factor beta1Carbon TetrachlorideMycophenolic AcidRNA, MessengerTransforming Growth Factor beta1collagen Ihepatic fibrosismycophenolate mofetiltransforming growth factor-β1α-smooth muscle actin

Identifiers

PMID37587066
PMCPMC10930439
OpenAlexW4385898342

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.