Evidence map›Paper›PMID 37587024›Full record

ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2023

Cumulative Stress Exposure and Cognitive Function Among Older Adults: The Moderating Role of a Healthy Lifestyle.

Danielle D'Amico, Udi Alter, Alexandra J Fiocco

Open access · greenAbstract read
In one paragraph

Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Cumulative stress and epigenetic aging: Examining the role of psychological moderators.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
    Article
  4. Social Engagement, Depressive Symptoms, and Loneliness, and Longitudinal Cognitive Decline in a Population-Based Cohort of Older Adults.The American journal of geriatric psychiatry. Open science, education, and practice · 2025
    Article
  5. Article
  6. Article
  7. Psychological Stress and Cognitive Brain Health: Policies to Reduce Dementia Risk.Policy insights from the behavioral and brain sciences · 2025
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Danielle D'AmicoInstitute of Stress and Wellbeing Research, Department of Psychology, Toronto Metropolitan University, Toronto, Ontario, Canada.ORCID 0000-0001-5345-2711
Udi AlterDepartment of Psychology, York University, Toronto, Ontario, Canada.
Alexandra J FioccoInstitute of Stress and Wellbeing Research, Department of Psychology, Toronto Metropolitan University, Toronto, Ontario, Canada.
Toronto Metropolitan University · CAYork University · CA

Funding

U19 MIDlife in the United States-Diversity Supplement-WellsU19AG051426 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI CAROL D. RYFF · 2016 to 2026
$74.8M
STATISTICS COREP01AG020166 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI RYFF, CAROL D. · 2002 to 2015
$50.6M
NIA NIH HHS P01 AG020166NIA NIH HHS U19-AG051426
6 · The paper itself

Abstract

objectivesAlthough chronic stress is a risk factor for poor age-related cognitive health, there is limited research that has examined how cumulative stress across the lifespan affects cognitive aging. There may also be resilience factors that minimize the effects of cumulative stress on cognitive health. Engaging in a healthy lifestyle is protective against cognitive decline and may therefore interact with cumulative stress to buffer the stress-cognition relationship. The objective of the current study was to examine the moderating role of a healthy lifestyle, comprised of physical activity, social engagement, and sleep quality, in the relationship between cumulative stress exposure (CSE) and baseline and change in cognitive performance (global cognition, episodic memory, executive function) over 9 years among 1,297 older adults in the Midlife in the United States cohort (Mage = 69.0 ± 6.4, 57.8% female).

methodsCSE and healthy lifestyle behaviors were indexed using self-reported questionnaires at baseline, and cognitive function was assessed using a battery of standardized neuropsychological tests at baseline and follow-up.

resultsControlling for age, sex, education, race, marital status, employment status, hypertension, diabetes, and depression, higher CSE was associated with poorer baseline performance and slower decline over time in global cognition and executive function, but not episodic memory. A healthy lifestyle did not significantly moderate the relationship between cumulative stress and cognitive function. Exploratory analyses showed a significant cumulative stress-cognition relationship among females only. DISCUSSION: This study lends support for a lifespan model of cognitive aging and suggests that the cognitive health consequences of stress extend beyond immediate timescales.

Indexed as

CognitionCognitive DysfunctionAgedExecutive FunctionFemaleHealthy LifestyleHumansLongitudinal StudiesMaleNeuropsychological TestsUnited StatesBrain healthCognitive agingLife courseLifestyleStress

Identifiers

PMID37587024
PMCPMC10699734
OpenAlexW4385852371

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.