Evidence map›Paper›PMID 37586864›Full record

ArticleBMJ open2023

Diagnostic Accuracy and economic value of a Tiered Assessment for Fetal Alcohol Spectrum Disorder (DATAforFASD): Protocol.

Dianne C Shanley, Melanie Zimmer-Gembeck, Amanda J Wheeler, Joshua Byrnes, Robert S Ware, Wei Liu, Gabrielle Simcock, Codi White, Sarah Horton, Marjad Page and 12 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 6 institutions in 2 countries.

Dianne C ShanleyMenzies Health Institute of Queensland, Griffith University, Gold Coast, Queensland, Australia d.shanley@griffith.edu.au.ORCID 0000-0002-3849-075X
Melanie Zimmer-GembeckMenzies Health Institute of Queensland, Griffith University, Gold Coast, Queensland, Australia.
Amanda J WheelerMenzies Health Institute of Queensland, Griffith University, Gold Coast, Queensland, Australia.ORCID 0000-0001-9755-674X
Joshua ByrnesMenzies Health Institute of Queensland, Griffith University, Gold Coast, Queensland, Australia.
Robert S WareMenzies Health Institute of Queensland, Griffith University, Gold Coast, Queensland, Australia.ORCID 0000-0002-6129-6736
Wei LiuMenzies Health Institute of Queensland, Griffith University, Gold Coast, Queensland, Australia.
Gabrielle SimcockMenzies Health Institute of Queensland, Griffith University, Gold Coast, Queensland, Australia.
Codi WhiteMenzies Health Institute of Queensland, Griffith University, Gold Coast, Queensland, Australia.
Sarah HortonFamily Health, Gidgee Healing, Mt Isa, Queensland, Australia.
Marjad PageMenzies Health Institute of Queensland, Griffith University, Gold Coast, Queensland, Australia.
Doug SheltonMenzies Health Institute of Queensland, Griffith University, Gold Coast, Queensland, Australia.
Haydn TillMenzies Health Institute of Queensland, Griffith University, Gold Coast, Queensland, Australia.
Ianthe MillsChild and Adolescent Unit, Sunshine Coast Hospital and Health Service, Nambour, Queensland, Australia.
Carly HislopChild Development Service, Townsville Hospital and Health Service, Townsville, Queensland, Australia.
Katrina HarrisVictorian Fetal Alcohol Service, Monash Children's Hospital, Clayton, Victoria, Australia.
Alison CrichtonVictorian Fetal Alcohol Service, Monash Children's Hospital, Clayton, Victoria, Australia.
Natasha ReidChild Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.
Sheena ReillyMenzies Health Institute of Queensland, Griffith University, Gold Coast, Queensland, Australia.
Karen MoritzFaculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.
Kerryann WalshSchool of Early Childhood and Inclusive Education, Queensland University of Technology, Brisbane, Queensland, Australia.
Sharyn Rundle-ThieleSocial Marketing, Griffith University, Nathan, Queensland, Australia.
Erinn HawkinsMenzies Health Institute of Queensland, Griffith University, Gold Coast, Queensland, Australia.
Griffith University · AUMonash Children’s Hospital · AUThe University of Queensland · AUHealing Foundation · AUQueensland University of Technology · AUTownsville Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAustralian practices for diagnosing fetal alcohol spectrum disorder (FASD) are lengthy and require specialist expertise. Specialist teams are based in urban locations; they are expensive and have prolonged waitlists. Innovative, flexible solutions are needed to ensure First Nations children living in rural/remote communities have culturally appropriate and equitable access to timely diagnosis and support. This study compares the accuracy of rapid assessments (index tests) that can be administered by a range of primary healthcare practitioners to specialist standardised FASD assessments (reference tests). The cost-efficiency of index tests will be compared with reference tests. METHODS AND ANALYSIS: At least 200 children aged 6-16 years at-risk of FASD will be recruited across at least seven study sites. Following standards for reporting diagnostic accuracy study (STARD) guidelines, all children will complete index and reference tests. Diagnostic accuracy statistics (including receiver operating curves, sensitivity, specificity, positive and negative predictive values and likelihood ratios) will identify whether rapid assessments can accurately identify: (1) the presence of an FASD diagnosis and (2) impairment in each neurodevelopmental domain, compared to comprehensive assessments. Direct and indirect healthcare costs for index tests compared to reference tests will be collected in primary healthcare and specialist settings. ETHICS AND DISSEMINATION OF

resultsChildren's Health Queensland Hospital and Health Service Human Research Ethics Committee (HREC/20/QCHQ/63173); Griffith University Human Research Ethics Committee (2020/743). Results will assist in validating the use of index tests as part of a tiered neurodevelopmental assessment process that was co-designed with First Nations community and primary healthcare practitioners. Outcomes will be summarised and provided to participating practitioners and sites, and disseminated to community health services and consumers. Findings will be presented at national and international conferences and published in peer-reviewed journals. TRIAL REGISTRATION NUMBER: ACTRN12622000498796.

Indexed as

Fetal Alcohol Spectrum DisordersAustraliaChildChild HealthFemaleHealth Care CostsHospitals, PediatricHumansPregnancyCommunity child healthDevelopmental neurology & neurodisabilityHEALTH ECONOMICSHealth Services AccessibilityPRIMARY CARE

Identifiers

PMID37586864
PMCPMC10432646
OpenAlexW4385863382

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.