ArticleThe British journal of ophthalmology2024
Descemet's membrane endothelial keratoplasty is the predominant keratoplasty procedure in Germany since 2016: a report of the DOG-section cornea and its keratoplasty registry.
Article in The British journal of ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03381794 (Trends in Corneal Transplantation From 2001 in Germany), which is not on this map. Cited by 31 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Trends in Corneal Transplantation From 2001 in Germany: Reports of the DOG-Section Cornea and Its Keratoplasty Registry
Who cites it
31 citing papers in PubMed.
- Article
- DMEK graft preparation techniques - liquid bubble technique compared to Melles technique.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Article
- Astigmatic changes after Descemet membrane endothelial keratoplasty (DMEK) in decompensated penetrating keratoplasty grafts.Acta ophthalmologica · 2026Article
- Learning curve and procedural standardization in liquid-bubble DMEK: impact on preparation efficiency, complication rates, and endothelial cell survival.International ophthalmology · 2026Article
- [How to … preparation of DMEK graft].Die Ophthalmologie · 2026Article
- Air/gas migration after descemet membrane endothelial keratoplasty (DMEK): the impact of scleral-fixated versus posterior chamber intraocular lenses.BMC ophthalmology · 2026Article
- [Multilevel revision after complicated cataract surgery. Video article].Die Ophthalmologie · 2026Review
- Impact of donor-recipient gender mismatch on outcomes in Descemet membrane endothelial keratoplasty (DMEK).Cell and tissue banking · 2026Article
- Avoiding Post-DMEK IOP Elevation: Insights from a Standardized Surgical Approach.Journal of clinical medicine · 2026Article
- DMEK grafts prepared from corneas stored in TISSUE-C and CARRY-C (deswelling medium) show similar viable endothelial cell density.Scientific reports · 2026Article
- Prescription patterns in DMEK: European survey.Journal of cataract and refractive surgery · 2025Article
- Impact of the Different Corneal Storage Flasks on Endothelial Cell Loss During Cultivation-A Retrospective Analysis.Journal of clinical medicine · 2025Article
- Visual and ultrastructural analysis after splitting of recipient's Descemet membrane during Descemet membrane endothelial keratoplasty.Eye (London, England) · 2025Observational
- Anterior segment optical coherence tomography (AS-OCT) assisted analysis of characteristics of graft dehiscence after Descemet membrane endothelial keratoplasty (DMEK) for failed penetrating keratoplasty.Acta ophthalmologica · 2025Article
- Effectiveness of enoxaparin in preventing intraoperative fibrin formation during DMEK assessed in a before-and-after study.Scientific reports · 2025Article
- A historical view of the development of corneal transplantation: from penetrating keratoplasty to selective transplantation of the finest corneal layers.Wiener medizinische Wochenschrift (1946) · 2025Review
- Optimized laboratory techniques for assessing the quality of pre-stripped DMEK grafts.Scientific reports · 2025Article
- Changing indications for keratoplasty: monocentric analysis of the past two decades.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- Bubble-graft coverage after Descemet Membrane Endothelial Keratoplasty depending on gaze angle.European journal of ophthalmology · 2025Observational
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsThis retrospective multicentric panel study provides absolute numbers, types of and indications for corneal transplantation in Germany from 2011 to 2021 and sets them into the international context.
methodsA questionnaire was sent to the 104 German ophthalmologic surgery departments and 93 (89%) provided their data.
resultsThe number of reported keratoplasties more than doubled from 2011 (n=4474) to 2021 (n=8998). Lamellar keratoplasties (49% posterior (n=2883), 4% anterior (n=231)) surpassed penetrating keratoplasty (PKP, 47%, n=2721) for the first time in 2014. Since 2016, Descemet's membrane endothelial keratoplasty (DMEK) has become the predominant keratoplasty procedure in Germany. Its number increased by 1.5-fold from 3850 (2016) to 5812 (2021). Main indications in 2021 were Fuchs' endothelial corneal dystrophy (FECD, 43%), pseudophakic corneal decompensation (12%), repeated keratoplasty (11%), infections (7%), keratoconus (6%) and corneal scarring (4%, others: 9%). The PKP percentage decreased from 70.2% in 2011 (n=3141) to 31.7% in 2021 (n=2853). Descemet's stripping (automated) endothelial keratoplasties (DSAEKs) decreased to 1% in 2021 (n=74). 98.6% of all posterior lamellar keratoplasties were DMEKs in Germany in 2021. The number of deep anterior lamellar keratoplasties (DALKs) remained comparable from 2011 (n=269) to 2021 (n=251, 2.8%).
conclusionMain indications for corneal transplantation in Germany (2021) were FECD and pseudophakic corneal decompensation. DMEK is by far the predominant corneal transplantation procedure since 2016 followed by PKP, whose absolute number decreased only slightly during the decade from 2011 to 2021. DALK proportions remain low, but stable, whereas DSAEK decreased annually and plays a minor role in Germany. TRIAL REGISTRATION NUMBER: NCT03381794.
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