Evidence map›Paper›PMID 37586445›Full record

ArticleNeuroImage2023

Frequency-dependent diffusion kurtosis imaging in the human brain using an oscillating gradient spin echo sequence and a high-performance head-only gradient.

Erpeng Dai, Ante Zhu, Grant K Yang, Kristin Quah, Ek T Tan, Eric Fiveland, Thomas K F Foo, Jennifer A McNab

Open access · goldAbstract read
In one paragraph

Article in NeuroImage, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

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  10. Engineering clinical translation of OGSE diffusion MRI.Magnetic resonance in medicine · 2025
    Review
  11. Review
  12. Article
  13. [Spherical measurement-based analysis of gradient nonlinearity in magnetic resonance imaging].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Erpeng DaiDepartment of Radiology, Stanford University, Stanford, CA, USA. Electronic address: daiep@stanford.edu.
Ante ZhuGE Research, Niskayuna, NY, USA.
Grant K YangDepartment of Radiology, Stanford University, Stanford, CA, USA; Department of Electrical Engineering, Stanford University, Stanford, CA, USA.
Kristin QuahDepartment of Radiology, Stanford University, Stanford, CA, USA; Department of Electrical Engineering, Stanford University, Stanford, CA, USA.
Ek T TanDepartment of Radiology and Imaging, Hospital for Special Surgery, New York, NY, USA.
Eric FivelandGE Research, Niskayuna, NY, USA.
Thomas K F FooGE Research, Niskayuna, NY, USA.
Jennifer A McNabDepartment of Radiology, Stanford University, Stanford, CA, USA.
GE Global Research (United States) · USStanford University · USHospital for Special Surgery · USStanford Medicine · US

Funding

Integration of Diffusion MRI Fiber Tracking and CLARITY 3D Histology for Improved Neurosurgical TargetingR01NS095985 · NINDS · STANFORD UNIVERSITY · PI Jennifer A McNab · 2016 to 2026
$3.8M
NINDS NIH HHS R01 NS095985
6 · The paper itself

Abstract

Measuring the time/frequency dependence of diffusion MRI is a promising approach to distinguish between the effects of different tissue microenvironments, such as membrane restriction, tissue heterogeneity, and compartmental water exchange. In this study, we measure the frequency dependence of diffusivity (D) and kurtosis (K) with oscillating gradient diffusion encoding waveforms and a diffusion kurtosis imaging (DKI) model in human brains using a high-performance, head-only MAGNUS gradient system, with a combination of b-values, oscillating frequencies (f), and echo time that has not been achieved in human studies before. Frequency dependence of diffusivity and kurtosis are observed in both global and local white matter (WM) and gray matter (GM) regions and characterized with a power-law model ∼Λ*f

Indexed as

Diffusion Tensor ImagingWhite MatterBrainDiffusion Magnetic Resonance ImagingGray MatterHumansDiffusion kurtosis imagingGradient nonlinearity correctionHigh-performance gradientOscillating gradient spin echoTime/frequency dependence

Identifiers

PMID37586445
PMCPMC10529993
OpenAlexW4385803985

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.