Evidence map›Paper›PMID 37586396›Full record

ArticleChemical senses2023

A quick test to objectify smell and taste dysfunction at home: a proof of concept for the validation of the chemosensory perception test.

Cindy Levesque-Boissonneault, Nicholas Bussière, Frédérique Roy-Côté, Frank Cloutier, Marie-Ève Caty, Johannes Frasnelli

Open access · greenAbstract read
In one paragraph

Article in Chemical senses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Cindy Levesque-BoissonneaultDepartment of Anatomy, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada.ORCID 0000-0002-6385-0243
Nicholas BussièreDepartment of Anatomy, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada.ORCID 0000-0002-1376-2421
Frédérique Roy-CôtéResearch Center of the Sacré-Cœur hospital, CIUSSS Nord-de-l'Île-de-Montréal, Montréal, QC, Canada.ORCID 0000-0001-8365-9801
Frank CloutierDepartment of Anatomy, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada.ORCID 0000-0002-6343-1639
Marie-Ève CatyDepartment of Speech and Language Pathology, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada.ORCID 0000-0003-3909-6639
Johannes FrasnelliDepartment of Anatomy, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada.ORCID 0000-0002-8863-3982
Université du Québec à Trois-Rivières · CACentre Intégré Universitaire de Santé et de Services Sociaux du Saguenay–Lac-Saint-Jean · CAKarolinska Institutet · SE

Funding

CIHR PJT 173514
6 · The paper itself

Abstract

Recent studies have shown the efficacy of a home test for the self-evaluation of olfactory and gustatory functions in quarantined coronavirus disease-2019 (COVID-19) patients. However, testing was often limited to COVID-19 participants, and the accuracy of home test kits was rarely compared to standardized testing. This study aims at providing proof of concept for the validation of the new Chemosensory Perception Test (CPT) developed to remotely assess orthonasal olfactory, retronasal olfactory, and gustatory functions in various populations using common North American household items. In the 2 experiments, a total of 121 participants irrespective of having olfactory and/or gustatory complaints from various causes (COVID-19, sinunasal, post-viral, idiopathic) were tested first, with one or many of the following tests: (i) a brief chemosensory questionnaire, (ii) an olfactory test-Sniffin' Sticks Test (SST) or University of Pennsylvania Smell Identification Test (UPSIT), and/or (iii) a gustatory test-Brief Waterless Empirical Taste Test (B-WETT). We then applied the CPT which yielded 3 different subscores, namely orthonasal, retronasal, and gustatory CPT scores. The orthonasal CPT score was significantly correlated with SST (ρ = 0.837, P < 0.001) and UPSIT (ρ = 0.364, P < 0.001) scores, and exhibited an excellent accuracy to identify olfactory dysfunction (OD) as compared to SST (area under the curve [AUC]: 0.923 [95% confidence interval {CI}, 0.822-1.000], P < 0.001). The retronasal CPT score but not the gustatory CPT score allowed to distinguish between participants with or without subjective gustatory complaint (AUC: 0.818 [95% CI, 0.726-0.909], P < 0.001). The CPT has the ability to identify OD and to quantify subjective gustatory complaints.

Indexed as

COVID-19Olfaction DisordersHumansSmellTasteTaste DisordersTaste Perceptionchemosensory testingCOVID-19home testpandemicremote testingself-assessment

Identifiers

PMID37586396
PMCPMC10746307
OpenAlexW4385852811

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.