Evidence map›Paper›PMID 37586274›Full record

ArticlePsychoneuroendocrinology2023

Titi monkey father-daughter bond-related behaviors explain stress response variability.

Lynea R Witczak, Jaclyn Samra, Madison Dufek, Leana R Goetze, Sara M Freeman, Rocío Arias-Del Razo, Alexander Baxter, Chloe Karaskiewicz, Allison R Lau, Emily S Rothwell and 3 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Psychoneuroendocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Lynea R WitczakDepartment of Psychology, University of California, Davis, Davis, CA 95616, USA; California National Primate Research Center, University of California, Davis, Davis, CA 95616, USA. Electronic address: lrwitczak@ucdavis.edu.
Jaclyn SamraDepartment of Psychology, University of California, Davis, Davis, CA 95616, USA.
Madison DufekCalifornia National Primate Research Center, University of California, Davis, Davis, CA 95616, USA.
Leana R GoetzeCalifornia National Primate Research Center, University of California, Davis, Davis, CA 95616, USA.
Sara M FreemanCalifornia National Primate Research Center, University of California, Davis, Davis, CA 95616, USA; Department of Biology, Utah State University, Logan, UT 84332, USA.
Rocío Arias-Del RazoDepartment of Psychology, University of California, Davis, Davis, CA 95616, USA; California National Primate Research Center, University of California, Davis, Davis, CA 95616, USA.
Alexander BaxterDepartment of Psychology, University of California, Davis, Davis, CA 95616, USA; California National Primate Research Center, University of California, Davis, Davis, CA 95616, USA.
Chloe KaraskiewiczDepartment of Psychology, University of California, Davis, Davis, CA 95616, USA; California National Primate Research Center, University of California, Davis, Davis, CA 95616, USA.
Allison R LauCalifornia National Primate Research Center, University of California, Davis, Davis, CA 95616, USA; Animal Behavior Graduate Group, University of California, Davis, Davis, CA 95616, USA.
Emily S RothwellCalifornia National Primate Research Center, University of California, Davis, Davis, CA 95616, USA; Animal Behavior Graduate Group, University of California, Davis, Davis, CA 95616, USA.
Logan E SavidgeDepartment of Psychology, University of California, Davis, Davis, CA 95616, USA; California National Primate Research Center, University of California, Davis, Davis, CA 95616, USA.
Emilio FerrerDepartment of Psychology, University of California, Davis, Davis, CA 95616, USA.
Karen L BalesDepartment of Psychology, University of California, Davis, Davis, CA 95616, USA; California National Primate Research Center, University of California, Davis, Davis, CA 95616, USA; Animal Behavior Graduate Group, University of California, Davis, Davis, CA 95616, USA; Department of Neurobiology, Physiology, and Behavior, University of California, Davis, Davis, CA 95616, USA.
University of California, Davis · USUtah State University · US

Funding

National Institute on Aging (NIA) ColonyP51OD011107 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Simon J. Atkinson · 2012 to 2026
$191.5M
THE NEURAL BASIS OF PAIR-BONDING IN FEMALE TITI MONKEYSR01HD092055 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BALES, KAREN L. · 2017 to 2021
$2.8M
NICHD NIH HHS R01 HD092055NIH HHS P51 OD011107
6 · The paper itself

Abstract

Social interactions regulate our behavior and physiology, and strong social bonds can buffer us from stress. Coppery titi monkeys (Plecturocebus cupreus) are socially monogamous South American monkeys that display strong social bonds. Infants form selective bonds with their fathers, making them ideal for studying father-daughter bonds. We established a method for quantifying variability in expression of bond-related behaviors in females (n = 12), and the present study is the second to use this method for explaining titi monkey responses to behavioral tests. We also investigated how manipulations of oxytocin (OT) and vasopressin (AVP) influenced juvenile behavior and physiology. Subjects received acute intranasal treatments of saline, low/medium/high OT, low/high AVP, or OT receptor antagonist (OTA) prior to an acute social separation. General linear mixed-effects model results revealed fathers were significant behavioral and physiological stress buffers for their daughters, as evidenced by fewer distress vocalizations (p < 0.001), less locomotion (p < 0.001), and lower plasma cortisol (p < 0.001) in a social separation paradigm. Females vocalized less if they exhibited greater expression of bond-related behaviors with their fathers as infants (p = 0.01), and this stress-buffering effect remained even when the daughter was separated from the father (p = 0.001). While treatments did not alter behaviors, OTA treatment caused the largest rise in plasma cortisol (p < 0.001), suggesting blockade of OT receptors can inhibit fathers' stress-buffering effects. Remarkably, females with greater expression of father-daughter bond-related behaviors exhibited an overall reduced physiological separation distress response (p = 0.04). Findings from the present study advance current knowledge of the neurobiological mechanisms foundational to female bonds and help inform how social disruptions may differently impact individuals based on expression of bond-related behaviors.

Indexed as

CallicebusPitheciidaeAnimalsFathersFemaleHumansHydrocortisoneMaleNuclear FamilyOxytocinReceptors, OxytocinSocial BehaviorHydrocortisoneOxytocinReceptors, OxytocinArginine-vasopressinCortisolOxytocinSeparation distressSocial bondStress buffering

Identifiers

PMID37586274
PMCPMC11759130
OpenAlexW4385740923

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.