Evidence map›Paper›PMID 37585464›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

TRPML3/BK complex promotes autophagy and bacterial clearance by providing a positive feedback regulation of mTOR via PI3P.

Mengnan Xu, Xi Zoë Zhong, Peng Huang, Dawid Jaślan, Pingping Wang, Xue Sun, Eva-Maria Weiden, Yassine El Hiani, Christian Grimm, Xian-Ping Dong

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. The ion channels of endomembranes.Physiological reviews · 2024
    Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Mengnan Xu *Department of Physiology and Biophysics, Dalhousie University, Halifax, NS B3H 4R2, Canada.
Xi Zoë Zhong *Department of Physiology and Biophysics, Dalhousie University, Halifax, NS B3H 4R2, Canada.
Peng Huang *Department of Physiology and Biophysics, Dalhousie University, Halifax, NS B3H 4R2, Canada.
Dawid Jaślan *Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, Ludwig-Maximilians-Universität, Munich 80336, Germany.ORCID 0000-0002-0685-7633
Pingping WangDepartment of Physiology and Biophysics, Dalhousie University, Halifax, NS B3H 4R2, Canada.
Xue SunDepartment of Physiology and Biophysics, Dalhousie University, Halifax, NS B3H 4R2, Canada.
Eva-Maria WeidenWalther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, Ludwig-Maximilians-Universität, Munich 80336, Germany.ORCID 0000-0001-9582-4448
Yassine El HianiDepartment of Physiology and Biophysics, Dalhousie University, Halifax, NS B3H 4R2, Canada.
Christian GrimmWalther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, Ludwig-Maximilians-Universität, Munich 80336, Germany.ORCID 0000-0002-0177-5559
Xian-Ping DongDepartment of Physiology and Biophysics, Dalhousie University, Halifax, NS B3H 4R2, Canada.
Dalhousie University · CALudwig-Maximilians-Universität München · DEFraunhofer Institute for Translational Medicine and Pharmacology · DE

Funding

CIHR PJT-156102
6 · The paper itself

Abstract

TRPML3 is a Ca

Indexed as

Large-Conductance Calcium-Activated Potassium ChannelsSirolimusAutophagyBacteriaFeedbackTOR Serine-Threonine KinasesLarge-Conductance Calcium-Activated Potassium ChannelsSirolimusTOR Serine-Threonine KinasesautophagyendolysosomemTORTRPML3

Identifiers

PMID37585464
PMCPMC10450854
OpenAlexW4385858505

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.