Evidence map›Paper›PMID 37585285›Full record

ArticleMolecular biology of the cell2023

Nuclear damage in

Melanie Wallace, Hind Zahr, Shriya Perati, Chloé D Morsink, Lindsey E Johnson, Anthony M Gacita, Shuping Lai, Lori L Wallrath, Ivor J Benjamin, Elizabeth M McNally and 2 more

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. A highly penetrantbioRxiv : the preprint server for biology · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Precise gene editing of pathogenic Lamin A mutations corrects cardiac disease.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Melanie WallaceMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853.
Hind ZahrWeill Institute for Cell and Molecular Biology, Ithaca, NY 14853.
Shriya PeratiWeill Institute for Cell and Molecular Biology, Ithaca, NY 14853.
Chloé D MorsinkDepartment of Physiology, Amsterdam University Medical Centers, Amsterdam Cardiovascular Sciences, Location VU Medical Center, 1081 HZ Amsterdam, The Netherlands.
Lindsey E JohnsonWeill Institute for Cell and Molecular Biology, Ithaca, NY 14853.
Anthony M GacitaCenter for Genetic Medicine, Feinberg School of Medicine, Northwestern Medicine, Chicago, IL 60611.
Shuping LaiCardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226.
Lori L WallrathDepartment of Biochemistry and Molecular Biology, University of Iowa, Iowa City, IA 52242.
Ivor J BenjaminCardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226.
Elizabeth M McNallyCenter for Genetic Medicine, Feinberg School of Medicine, Northwestern Medicine, Chicago, IL 60611.
Tyler J KirbyWeill Institute for Cell and Molecular Biology, Ithaca, NY 14853.
Jan LammerdingMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853.
Amsterdam University Medical Centers · NLCornell University · USMedical College of Wisconsin · USNorthwestern Medicine · USUniversity of Iowa · US

Funding

Cardiomyopathy Genomes ProjectR01HL128075 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MCNALLY, ELIZABETH M, NOBREGA, MARCELO A. · 2015 to 2023
$5.3M
Nuclear mechanics and mechanotransduction in muscular laminopathiesR01HL082792 · NHLBI · CORNELL UNIVERSITY · PI LAMMERDING, JAN · 2007 to 2023
$4.8M
Defining regulatory regions for cardiomyopathy genesF30HL142187 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GACITA, ANTHONY MARTIN · 2018 to 2021
$192k
NHLBI NIH HHS F30 HL142187NHLBI NIH HHS R01 HL082792NHLBI NIH HHS R01 HL128075
6 · The paper itself

Abstract

The

Identifiers

PMID37585285
PMCPMC10846625
OpenAlexW4385872202

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.