Evidence map›Paper›PMID 37585105›Full record

ArticleJournal of proteome research2023

Proteomic Investigation of Differential Interactomes of Glypican 1 and a Putative Disease-Modifying Variant of Ataxia.

Nur Cengiz Winter, Mert Karakaya, Peter Mosen, Isabell Brusius, Banu Anlar, Goknur Haliloglu, Dominic Winter, Brunhilde Wirth

Open access · hybridAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of proteome research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 72% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Nur Cengiz WinterInstitute of Human Genetics, University Hospital Cologne, 50931 Cologne, Germany.
Mert KarakayaInstitute of Human Genetics, University Hospital Cologne, 50931 Cologne, Germany.
Peter MosenInstitute for Biochemistry and Molecular Biology, Medical Faculty, University of Bonn, 53115 Bonn, Germany.
Isabell BrusiusInstitute of Human Genetics, University Hospital Cologne, 50931 Cologne, Germany.
Banu AnlarDepartment of Pediatrics, Division of Pediatric Neurology, Hacettepe University Faculty of Medicine, 06230 Ankara, Turkey.
Goknur HalilogluDepartment of Pediatrics, Division of Pediatric Neurology, Hacettepe University Faculty of Medicine, 06230 Ankara, Turkey.
Dominic WinterInstitute for Biochemistry and Molecular Biology, Medical Faculty, University of Bonn, 53115 Bonn, Germany.
Brunhilde WirthInstitute of Human Genetics, University Hospital Cologne, 50931 Cologne, Germany.ORCID 0000-0003-4051-5191
University of Cologne · DEHacettepe University · TRUniversity of Bonn · DEUniversity Hospital Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a currently 13-year-old girl of consanguineous Turkish parents, who developed unsteady gait and polyneuropathy at the ages of 3 and 6 years, respectively, we performed whole genome sequencing and identified a biallelic missense variant c.424C>T, p.R142W in glypican 1 (

Indexed as

Friedreich AtaxiaProteomicsAdolescentAtaxiaChromatography, LiquidFemaleGlypicansHumansIron-Binding ProteinsTandem Mass SpectrometryGlypicansIron-Binding Proteinsdisease modifierFriedreich’s ataxiaGPC1GPC1 interactomeMS-based proteomicsneuromuscular disorder

Identifiers

PMID37585105
PMCPMC10476613
OpenAlexW4385851501

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.