Evidence map›Paper›PMID 37584689›Full record

ArticleThe Journal of organic chemistry2023

Supramolecular Regulation of Catalytic Activity in Molecularly Responsive Catalysts.

Ishani Bose, Yan Zhao

Abstract read
In one paragraph

Article in The Journal of organic chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ishani BoseDepartment of Chemistry, Iowa State University, Ames, Iowa 50011-3111, United States.ORCID 0000-0001-9995-9884
Yan ZhaoDepartment of Chemistry, Iowa State University, Ames, Iowa 50011-3111, United States.ORCID 0000-0003-1215-2565

Funding

Artificial Glycosidase with Controlled SelectivityR01GM138427 · NIGMS · IOWA STATE UNIVERSITY · PI ZHAO, YAN · 2020 to 2023
$1.3M
NIGMS NIH HHS R01 GM138427
6 · The paper itself

Abstract

Some enzymes switch between an open form and a closed form. We report a molecularly tuned catalyst that accommodates a substrate and a signal molecule simultaneously. Binding of the signal molecule helps direct the reactive group of the substrate to the catalytic group and enhances the catalytic activity. Subtle structural changes in either the substrate or the signal molecule are readily detected. The switching mechanism also allows the catalytic reaction to be turned on and off reversibly by specific molecular signals.

Identifiers

PMID37584689
PMCPMC11095615

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.