Evidence map›Paper›PMID 37584586›Full record

ArticleJournal of cognitive neuroscience2023

Association of Intrinsic Functional Connectivity between the Locus Coeruleus and Salience Network with Attentional Ability.

Joshua Neal, Inuk Song, Benjamin Katz, Tae-Ho Lee

Open access · greenAbstract read
In one paragraph

Article in Journal of cognitive neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Joshua NealVirginia Tech, Blacksburg.ORCID 0000-0003-0376-3057
Inuk SongVirginia Tech, Blacksburg.
Benjamin KatzVirginia Tech, Blacksburg.
Tae-Ho LeeVirginia Tech, Blacksburg.ORCID 0000-0001-6458-0620
Virginia Tech · US

Funding

Losing specificity: the role of the locus coeruleus in age-related distractibilityR01AG075000 · NIA · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI KATZ, BENJAMIN D, KIM, IL HWAN · 2022 to 2024
$2.3M
NIA NIH HHS R01 AG075000NIA NIH HHS R01AG075000
6 · The paper itself

Abstract

The locus coeruleus (LC) is a brainstem region associated with broad neural arousal because of norepinephrine production, but it has increasingly been associated with specific cognitive processes. These include sustained attention, with deficits associated with various neuropsychological disorders. Neural models of attention deficits have focused on interrupted dynamics between the salience network (SAL) with the frontoparietal network, which has been associated with task-switching and processing of external stimuli, respectively. Conflicting findings for these regions suggest the possibility of upstream signaling leading to attention dysfunction, and recent research suggests LC involvement. In this study, resting-state functional connectivity and behavioral performance on an attention task was examined within 584 individuals. Analysis revealed significant clusters connected to LC activity in the SAL. Given previous findings that attention deficits may be caused by SAL network switching dysfunctions, findings here further suggest that dysfunction in LC-SAL connectivity may impair attention.

Indexed as

Locus CoeruleusMagnetic Resonance ImagingArousalBrain StemHumansNeural Pathways

Identifiers

PMID37584586
PMCPMC11311826
OpenAlexW4385850498

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.