ArticleCureus2023
Olfactory Dysfunction as a Marker for Essential Hypertension in a Drug-Naive Adult Population: A Hospital-Based Study.
Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.
- Olfactory Dysfunction and Metabolic Syndrome Components: A Systematic Review and Meta-Analysis.The Laryngoscope · 2026Pooled it
- High Pesticide Exposure Events and Self-Reported and Measured Olfactory Dysfunction.JAMA otolaryngology-- head & neck surgery · 2026Article
- Genome-wide association analysis of hypertension and epigenetic aging reveals shared genetic architecture and identifies novel risk loci.Scientific reports · 2024Article
- Olfactory function in diabetes mellitus.Journal of clinical & translational endocrinology · 2024Review
- Inflammation and olfactory loss are associated with at least 139 medical conditions.Frontiers in molecular neuroscience · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveEssential hypertension is a leading cause of cardiovascular morbidity worldwide, but its precise etiology remains unclear. Although its prevalence is high, there is no established predictor for the condition at an early age. Recent research has suggested that olfactory function may be associated with blood pressure regulation. This study sought to explore the association between olfactory function and essential hypertension.
methodsThirty middle-aged volunteers of both sexes with essential hypertension were recruited for the study along with 30 healthy control subjects matched for age and demographic characteristics. Participants completed a demographic questionnaire and then underwent olfactory function tests to assess odor threshold and identification using the Indian Smell Identification Test (InSIT). The researchers calculated a combined threshold-identification score for both groups and performed the statistical analysis.
resultsThe study group showed significant olfactory scores in comparison to the control group participants. Control group showed a significantly higher mean combined olfactory score than the study population (p = 0.03). Significant negative correlation between systolic blood pressure and olfactory function (Pearson's coefficient = -0.329, p = 0.011) and a similar significant negative correlation between diastolic blood pressure and olfactory function (Pearson's coefficient = -0.252, p = 0.052) were the other observations. Gender differences did not account for any difference in the smell sense.
conclusionsThere may be a connection between olfactory function and blood pressure regulation in individuals with essential hypertension. However, further research is needed to better understand this association and to determine whether olfactory function could be used as a predictor or marker for hypertension.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.