Evidence map›Paper›PMID 37583677›Full record

ArticleDEN open2024

Clinical outcomes of endoscopic submucosal dissection for large pedunculated colorectal carcinoma: A retrospective multicenter study.

Katsuaki Inagaki, Ken Yamashita, Shiro Oka, Fumiaki Tanino, Noriko Yamamoto, Yuki Kamigaichi, Hirosato Tamari, Tomoyuki Nishimura, Yuki Okamoto, Hidenori Tanaka and 5 more

Open access · goldAbstract read
In one paragraph

Article in DEN open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Katsuaki InagakiDepartment of Gastroenterology Hiroshima University Hospital Hiroshima Japan.ORCID https://orcid.org/0000-0002-6000-1027
Ken YamashitaDepartment of Endoscopy Hiroshima University Hospital Hiroshima Japan.
Shiro OkaDepartment of Gastroenterology Hiroshima University Hospital Hiroshima Japan.ORCID https://orcid.org/0000-0002-1652-0743
Fumiaki TaninoDepartment of Gastroenterology Hiroshima University Hospital Hiroshima Japan.
Noriko YamamotoDepartment of Gastroenterology Hiroshima University Hospital Hiroshima Japan.
Yuki KamigaichiDepartment of Gastroenterology Hiroshima University Hospital Hiroshima Japan.
Hirosato TamariDepartment of Gastroenterology Hiroshima University Hospital Hiroshima Japan.
Tomoyuki NishimuraDepartment of Gastroenterology Hiroshima University Hospital Hiroshima Japan.ORCID https://orcid.org/0000-0002-0018-5960
Yuki OkamotoDepartment of Gastroenterology Hiroshima University Hospital Hiroshima Japan.
Hidenori TanakaDepartment of Endoscopy Hiroshima University Hospital Hiroshima Japan.ORCID https://orcid.org/0000-0002-3646-5796
Takahiro KotachiDepartment of Endoscopy Hiroshima University Hospital Hiroshima Japan.
Ryo YugeDepartment of Endoscopy Hiroshima University Hospital Hiroshima Japan.
Yuji UrabeDivision of Regeneration and Medicine Center for Translational and Clinical Research Hiroshima University Hospital Hiroshima Japan.
Yasuhiko KitadaiDepartment of Health Sciences Prefectural University of Hiroshima Hiroshima Japan.
Shinji TanakaDepartment of Endoscopy Hiroshima University Hospital Hiroshima Japan.
Hiroshima University Hospital · JPPrefectural University of Hiroshima · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Complete en-bloc resection of pedunculated colorectal carcinoma is necessary for a proper pathological diagnosis. However, due to poor visibility, large pedunculated colorectal carcinomas are difficult to snare and resect en-bloc using endoscopic resection or polypectomy. Additionally, the bleeding risk of large pedunculated colorectal carcinomas is relatively high. We aimed to assess the feasibility and safety of endoscopic submucosal dissection for large pedunculated colorectal carcinomas. Methods: We conducted a retrospective multicenter cohort study to assess 36 consecutive patients with 36 large pedunculated colorectal carcinomas who underwent endoscopic submucosal dissection and evaluated the outcomes of endoscopic submucosal dissection. Furthermore, patients were divided into two groups according to the procedure time, and the factors related to the procedure time were assessed. Results: The mean tumor size was 34.1 ± 9.9 mm. The en-bloc, complete en-bloc, and curative resection rates were 97% (35/36), 97% (35/36), and 81% (29/36), respectively. The rate of severe bleeding during the procedure was 11% (4/36); however, it could be controlled endoscopically in all patients. The rate of intraoperative perforation and delayed bleeding was 0% (0/36). Delayed perforations occurred in one patient that required surgery. A long procedure time was correlated with the location of the flexure and poor endoscope operability. No recurrence was observed in any patient. None of the patients died of colorectal carcinoma. Conclusions: Our results showed the feasibility and safety of endoscopic submucosal dissection for large pedunculated colorectal carcinomas.

Indexed as

colorectal neoplasmscomplicationsendoscopic submucosal dissectionlarge pedunculated colorectal carcinomatreatment outcome

Identifiers

PMID37583677
PMCPMC10423853
OpenAlexW4385808078

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.