Evidence map›Paper›PMID 37582707›Full record

Observational studyBMC psychiatry2023

Validation of the Generalized Anxiety Disorder-7 in patients with COPD: a cross-sectional study.

Meishan Liu, Dong Wang, Jiexin Fang, Yuhan Chang, Yongdong Hu, Kewu Huang

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Meishan LiuDepartment of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, No 8, Gongti South Road, 100020, Chaoyang District, Beijing, PR China.
Dong WangDepartment of Clinical Psychology, Beijing Chao-Yang Hospital, Capital Medical University, No 8, Gongti South Road, 100020, Chaoyang District, Beijing, PR China.
Jiexin FangDepartment of Clinical Psychology, Beijing Chao-Yang Hospital, Capital Medical University, No 8, Gongti South Road, 100020, Chaoyang District, Beijing, PR China.
Yuhan ChangDepartment of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, No 8, Gongti South Road, 100020, Chaoyang District, Beijing, PR China.
Yongdong HuDepartment of Clinical Psychology, Beijing Chao-Yang Hospital, Capital Medical University, No 8, Gongti South Road, 100020, Chaoyang District, Beijing, PR China. huyongdong@bjcyh.com.
Kewu HuangDepartment of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, No 8, Gongti South Road, 100020, Chaoyang District, Beijing, PR China. kewuhuang@126.com.
Beijing Chao-Yang Hospital · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with chronic obstructive pulmonary disease (COPD) often have comorbid generalized anxiety disorder (GAD), which requires early screening in respiratory clinics. The Generalized Anxiety Disorder-7 (GAD-7) questionnaire is a brief and commonly used screening tool for GAD but has not been validated among patients with COPD in China.

methodsStable patients with COPD from a cross-sectional observational study were assessed using the GAD-7 questionnaire and then assessed by a senior psychiatrist to confirm a diagnosis of GAD according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. Demographic characteristics, spirometry, and patient-reported outcomes were collected. Cronbach's α coefficient was calculated, and receiver operating curve (ROC) analysis was performed to validate the GAD-7.

resultsA total of 226 patients with COPD were enrolled, and 50 (22.1%) of these patients were diagnosed with GAD. The Cronbach's α coefficient for the GAD-7 was 0.869, which indicated good internal consistency. ROC curve analysis showed that the GAD-7 had an area under the curve (AUC) value of 0.829 (95% CI: 0.774-0.876) for identifying GAD. The optimal cut-off score was ≥ 4, with a sensitivity of 66.0% and a specificity of 89.2%. Higher GAD-7 scores were significantly associated with health-related quality of life and the symptom burden of COPD. The discriminatory power of GAD-7 did not differ statistically when stratified by COPD severity.

conclusionsThe GAD-7 was shown to be a reliable and valid screening tool for patients with COPD in China, and its screening performance for GAD was not influenced by disease severity.

Indexed as

Pulmonary Disease, Chronic ObstructiveQuality of LifeAnxietyAnxiety DisordersCross-Sectional StudiesHumansPsychometricsReproducibility of ResultsSurveys and QuestionnairesChronic obstructive pulmonary diseaseGAD-7Generalized anxiety disorderScreeningValidation

Identifiers

PMID37582707
PMCPMC10428582
OpenAlexW4385839563

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.