Evidence map›Paper›PMID 37581760›Full record

ArticleSleep & breathing = Schlaf & Atmung2024

The relationship between irritable bowel syndrome, the gut microbiome, and obstructive sleep apnea: the role of the gut-brain axis.

Ellen M S Xerfan, Anamaria S Facina, Jane Tomimori, Sergio Tufik, Monica L Andersen

Abstract readLetter
PubMed Publisher
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ellen M S XerfanPrograma de Pós-Graduação em Medicina Translacional, Departamento de Medicina, Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.
Anamaria S FacinaDepartamento de Dermatologia, Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP), Rua dos Otonis, 861 - Vila Clementino, São Paulo, 04025-002, Brazil. anamaria.facina@unifesp.br.ORCID 0000-0002-2888-7227
Jane TomimoriDepartamento de Dermatologia, Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP), Rua dos Otonis, 861 - Vila Clementino, São Paulo, 04025-002, Brazil.
Sergio TufikDepartamento de Psicobiologia, Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.
Monica L AndersenDepartamento de Psicobiologia, Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.
Universidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sleep disruption, especially that resulting from obstructive sleep apnea (OSA) - a widely prevalent sleep disorder - can lead to important systemic repercussions. We raise a subject of current interest, namely the possible relationship between sleep in general, OSA, and irritable bowel syndrome (IBS), an intestinal disease that can be made worse by stressful events. The intermittent hypoxia caused by OSA can induce alterations in the gut microbiota, which can lead to the dysregulation of the gut-brain axis and the worsening of IBS. This may be considered to be a circular relationship, with OSA playing a crucial role in the worsening of bowel symptoms, which in turn have a negative effect on sleep. Thus, based on previous evidence, we suggest that improving sleep quality could be a key to disrupting this relationship of IBS aggravation and OSA.

Indexed as

Gastrointestinal MicrobiomeIrritable Bowel SyndromeSleep Apnea, ObstructiveBrain-Gut AxisHumansSleepCOVID-19Gut-brain axisGut microbiomeIrritable bowel syndromeObstructive sleep apneaSleepSleep disorders

Identifiers

PMID37581760
OpenAlexW4385827198

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.