Evidence map›Paper›PMID 37581651›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2023

Increased risk of glaucoma development in patients with central serous chorioretinopathy: results of a 11-year population-based cohort study.

Yu-Te Huang, Lei Wan, Yih-Dih Cheng, Teng-Shun Yu, Yu-Tung Hung, Kewalee Rujikajorn, Jamie Jiin-Yi Chen, Ming-Yen Wu, Fuu-Jen Tsai, Hui-Ju Lin and 1 more

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In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Yu-Te HuangEye Center, China Medical University Hospital, Taichung, 40402, Taiwan.
Lei WanSchool of Chinese Medicine, China Medical University, Taichung, 40402, Taiwan.
Yih-Dih ChengSchool of Pharmacy, China Medical University, Taichung, Taiwan.
Teng-Shun YuManagement Office for Health Data, China Medical University Hospital, Taichung, Taiwan.
Yu-Tung HungManagement Office for Health Data, China Medical University Hospital, Taichung, Taiwan.
Kewalee RujikajornDepartment of General Medicine, Medical University of Lublin, Bangkok, Thailand.
Jamie Jiin-Yi ChenEye Center, China Medical University Hospital, Taichung, 40402, Taiwan.
Ming-Yen WuEye Center, China Medical University Hospital, Taichung, 40402, Taiwan.
Fuu-Jen TsaiSchool of Chinese Medicine, China Medical University, Taichung, 40402, Taiwan.
Hui-Ju LinEye Center, China Medical University Hospital, Taichung, 40402, Taiwan. irisluu2396@gmail.com.ORCID http://orcid.org/0000-0003-2606-8540
Peng-Tai TienEye Center, China Medical University Hospital, Taichung, 40402, Taiwan. miketien913@gmail.com.
China Medical University · TWBangkok University · TH

Funding

China Medical University Hospital DMR-111-105Ministry of Health and Welfare MOHW111-TDU-B-212-134004
6 · The paper itself

Abstract

purposeTo investigate whether patients with central serous chorioretinopathy (CSC) have increased risk of developing glaucoma.

methodsPatients diagnosed with CSC between 1 January 2008 and 31 December 2018 were included in this study using data from the Taiwanese National Health Insurance Research Database (NHIRD). The CSC cohort was matched with a non-CSC cohort using the propensity score matching method, based on sex, age (in 10-year intervals), index date year, comorbidities, and steroid use, resulting in equal numbers of patients in both cohorts. Patients were followed up until 31 December 2019 or until they were withdrawn from the NHIRD. The incidence of glaucoma was compared between the two cohorts using the Cox regression model, and the risk of developing glaucoma was estimated using the Kaplan-Meier method.

resultsAfter adjusting for sex, age, comorbidities, and steroid use, the CSC cohort showed a significantly higher risk of developing glaucoma compared to those without CSC (adjusted HR = 3.99; 95% CI = 3.44-4.62). The cumulative incidence of glaucoma in the CSC cohort was also significantly higher than in the non-CSC cohort (log-rank test, p < 0.001). Among the glaucoma subtypes, normal tension glaucoma had the highest risk (adjusted HR = 5.79; 95% CI = 3.41-9.85), followed by primary open-angle glaucoma (adjusted HR = 2.77; 95% CI = 2.12-3.62).

conclusionsIn conclusion, our study shows that CSC patients are at a higher risk of developing glaucoma, especially NTG. Awareness and regular glaucoma screenings are essential for patients with CSC.

Indexed as

Central Serous ChorioretinopathyGlaucomaGlaucoma, Open-AngleCohort StudiesHumansRetrospective StudiesRisk FactorsSteroidsSteroidsCentral serous chorioretinopathyGlaucomaPopulation-based cohort study

Identifiers

PMID37581651
OpenAlexW4385827237

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.