Evidence map›Paper›PMID 37581585›Full record

ArticleJournal of neurosurgery. Case lessons2023

Pediatric brainstem abscess successfully treated with stereotactic aspiration: illustrative case.

Nahom Teferi, Ajmain Chowdhury, Sarah Lee, Meron Challa, Lukasz Weiner, Sarah Auerbach, Mahil Rao, Brian J Dlouhy

Abstract read
In one paragraph

Article in Journal of neurosurgery. Case lessons, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nahom Teferi1Department of Neurosurgery, University of Iowa, Iowa City, Iowa.
Ajmain Chowdhury2University of Iowa, Carver College of Medicine, Iowa City, Iowa.
Sarah Lee1Department of Neurosurgery, University of Iowa, Iowa City, Iowa.
Meron Challa2University of Iowa, Carver College of Medicine, Iowa City, Iowa.
Lukasz Weiner3Department of Pediatrics, Division of Infectious Disease, University of Iowa, Iowa City, Iowa; and.
Sarah Auerbach3Department of Pediatrics, Division of Infectious Disease, University of Iowa, Iowa City, Iowa; and.
Mahil Rao4Department of Pediatrics, Division of Critical Care Medicine, University of Iowa, Iowa City, Iowa; and.
Brian J Dlouhy1Department of Neurosurgery, University of Iowa, Iowa City, Iowa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPediatric brainstem abscesses are rare entities that account for 1% of all brain abscesses and, when diagnosed, constitute a neurosurgical emergency. OBSERVATIONS: A previously healthy 11-year-old male presented with several days of worsening headache, confusion, and ataxia. Brain magnetic resonance imaging (MRI) revealed a midbrain and pons lesion. The patient subsequently had a rapid neurological decline with loss of consciousness and brainstem function. Follow-up MRI revealed significant enlargement of the brainstem lesion with extension into the pons, midbrain, and thalamus, with greater concerns for an abscess rather than a tumor or an inflammatory process. He was taken for an emergent stereotactic aspiration of the abscess, and broad-spectrum antibiotics were initiated. He had neurological improvement, which subsequently declined 5 days later with brain MRI revealing an increase in the brainstem abscess, which required a second stereotactic aspiration. After rehabilitation, he made a significant neurological recovery. LESSONS: Pediatric brainstem abscesses are rare pathologies, and a high index of suspicion is needed in patients presenting with a brainstem lesion mimicking tumor but with rapid neurological decline despite no other evidence of infection or infectious/inflammatory markers. Stereotactic aspiration is required for large lesions to target the antibiotic treatment and as an adjunct to broad-spectrum antibiotics.

Indexed as

brainstem abscessbroad-spectrum antibioticscranial nerve palsypolymicrobial infectionstereotactic aspiration

Identifiers

PMID37581585
PMCPMC10555595

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.