Evidence map›Paper›PMID 37581521›Full record

ReviewCurrent medicinal chemistry2025

Reproductive Toxicity of Nanoparticles: A Comprehensive Review.

Elaheh Mohammadi, Behzad Behnam, Ahad Mokhtarzadeh, Ramin Rezaee, Ardavan Abiri, Mohammad Ramezani, John P Giesy, Amirhossein Sahebkar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Is Emerging Nanomedicine a Friend or Foe to Germ Cells?International journal of nanomedicine · 2025
    Review
  4. Review
  5. A Review of in vivo Toxicity of Quantum Dots in Animal Models.International journal of nanomedicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Elaheh MohammadiStudents Research Committee, Faculty of Pharmacy, Kerman University of Medical Sciences, Kerman, Iran.
Behzad BehnamPharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.
Ahad MokhtarzadehImmunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Ramin RezaeeInternational UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Ardavan AbiriProgram in Computational Biology and Bioinformatics, Yale University, New Haven, CT06520, USA.
Mohammad RamezaniPharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
John P GiesyToxicology Centre, Department of Veterinary Biomedical Sciences, University of Saskatchewan, 10 Campus Drive, Saskatoon, SKS7N 5B4, Canada.
Amirhossein SahebkarBiotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Mashhad University of Medical Sciences · IRAhvaz Jundishapur University of Medical Sciences · IRBaylor University · USTabriz University of Medical Sciences · IR

Funding

Kerman University of Medical Sciences 98001136
6 · The paper itself

Abstract

The unique characteristics of nanoparticles (NPs) have captivated scientists in various fields of research. However, their safety profile has not been fully scrutinized. In this regard, the effects of NPs on the reproductive system of animals and humankind have been a matter of concern. In this article, we will review the potential reproductive toxicity of various types of NPs, including carbon nanomaterials, dendrimers, quantum dots, silica, gold, and magnetic nanoparticles, reported in the literature. We also mention some notable cases where NPs have elicited beneficial effects on the reproductive system. This review provides extensive insight into the effects of various NPs on sperm and ovum and the outcomes of their passage through blood-testis and placental barriers and accumulation in the reproductive organs.

Indexed as

NanoparticlesReproductionAnimalsDendrimersHumansDendrimersdendrimersnanomaterialsNanoparticlesnanosafetynanotoxicologyreproductive toxicity

Identifiers

PMID37581521
OpenAlexW4385827625

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.