Evidence map›Paper›PMID 37581386›Full record

ArticleJournal of the American Heart Association2023

Associations of Oral Contraceptive Use With Cardiovascular Disease and All-Cause Death: Evidence From the UK Biobank Cohort Study.

Weijuan Dou, Yan Huang, Xuesong Liu, Chensihan Huang, Junlin Huang, Bingyan Xu, Linjie Yang, Yating Liu, Xuzhen Lei, Xu Li and 7 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Brazilian Guideline on Menopausal Cardiovascular Health - 2024.Arquivos brasileiros de cardiologia · 2024
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  17. Brazilian Guideline on Menopausal Cardiovascular Health - 2024.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 1 country.

Weijuan DouDepartment of Endocrinology and Metabolism, Nanfang Hospital Southern Medical University Guangzhou China.ORCID 0000-0002-3754-1068
Yan HuangDepartment of Endocrinology and Metabolism, Nanfang Hospital Southern Medical University Guangzhou China.
Xuesong LiuState Key Lab of Respiratory Diseases, Guangzhou Institute of Respiratory Health, Department of Critical Care Medicine The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.
Chensihan HuangDepartment of Endocrinology and Metabolism, Nanfang Hospital Southern Medical University Guangzhou China.
Junlin HuangDepartment of Endocrinology and Metabolism, Nanfang Hospital Southern Medical University Guangzhou China.
Bingyan XuDepartment of Endocrinology and Metabolism, Nanfang Hospital Southern Medical University Guangzhou China.ORCID 0000-0002-9162-5692
Linjie YangDepartment of Endocrinology and Metabolism, Nanfang Hospital Southern Medical University Guangzhou China.
Yating LiuDepartment of Endocrinology and Metabolism, Nanfang Hospital Southern Medical University Guangzhou China.
Xuzhen LeiDepartment of Endocrinology and Metabolism, Nanfang Hospital Southern Medical University Guangzhou China.ORCID 0000-0001-8007-5296
Xu LiDepartment of Endocrinology and Metabolism, Nanfang Hospital Southern Medical University Guangzhou China.
Junfeng HuangDepartment of Endocrinology and Metabolism, Nanfang Hospital Southern Medical University Guangzhou China.ORCID 0009-0008-4308-8846
Jiayang LinDepartment of Endocrinology and Metabolism, Nanfang Hospital Southern Medical University Guangzhou China.ORCID 0000-0001-9887-976X
Deying LiuDepartment of Endocrinology and Metabolism, Nanfang Hospital Southern Medical University Guangzhou China.
Peizhen ZhangDepartment of Endocrinology and Metabolism, Nanfang Hospital Southern Medical University Guangzhou China.
Jiaqing ShaoDepartment of Endocrinology, Jinling Hospital Medical School of Nanjing University Nanjing China.
Changqin LiuDepartment of Endocrinology and Metabolism The First Affiliated Hospital of Xiamen University Xiamen China.
Huijie ZhangDepartment of Endocrinology and Metabolism, Nanfang Hospital Southern Medical University Guangzhou China.ORCID 0000-0003-0640-0315
Nanfang Hospital · CNKey Laboratory of Guangdong Province · CNNanjing General Hospital of Nanjing Military Command · CNFirst Affiliated Hospital of Guangzhou Medical University · CNFirst Affiliated Hospital of Xiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background The associations of oral contraceptive (OC) use with cardiovascular disease (CVD) and all-cause death remains unclear. We aimed to determine the associations of OC use with incident CVD and all-cause death. Methods and Results This cohort study included 161 017 women who had no CVD at baseline and reported their OC use. We divided OC use into ever use and never use. Cox proportional hazard models were used to calculate hazard ratios and 95% CIs for cardiovascular outcomes and death. Overall, 131 131 (81.4%) of 161 017 participants reported OC use at baseline. The multivariable-adjusted hazard ratios for OC ever users versus never users were 0.92 (95% CI, 0.86-0.99) for all-cause death, 0.91 (95% CI, 0.87-0.96) for incident CVD events, 0.88 (95% CI, 0.81-0.95) for coronary heart disease, 0.87 (95% CI, 0.76-0.99) for heart failure, and 0.92 (95% CI, 0.84-0.99) for atrial fibrillation. However, no significant associations of OC use with CVD death, myocardial infarction, or stroke were observed. Furthermore, the associations of OC use with CVD events were stronger among participants with longer durations of use (

Indexed as

Cardiovascular DiseasesBiological Specimen BanksCohort StudiesContraceptives, OralFemaleHumansRisk FactorsUnited KingdomContraceptives, Oralall‐cause deathcardiovascular diseaseoral contraceptive usewomen's health

Identifiers

PMID37581386
PMCPMC10492942
OpenAlexW4385724192

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.