Evidence map›Paper›PMID 37581167›Full record

ArticleInfection and drug resistance2023

Using Machine Learning to Predict Surgical Site Infection After Lumbar Spine Surgery.

Tianyou Chen, Chong Liu, Zide Zhang, Tuo Liang, Jichong Zhu, Chenxing Zhou, Shaofeng Wu, Yuanlin Yao, Chengqian Huang, Bin Zhang and 6 more

Abstract read
In one paragraph

Article in Infection and drug resistance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Multimodal imaging fusion and machine learning model development: differential diagnosis of spinal inflammatory lesions using combined CT hounsfield units and MRI features.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Development and validation of machine learning models to predict vertebral artery injury by C2 pedicle screws.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Tianyou Chen *Department of Spine and Osteopathy Ward, the First Affiliated Hospital of Guangxi Medical University, Nanning, People's Republic of China.
Chong LiuDepartment of Spine and Osteopathy Ward, the First Affiliated Hospital of Guangxi Medical University, Nanning, People's Republic of China.
Zide ZhangSpine Ward, Liuzhou People's Hospital, Liuzhou, People's Republic of China.
Tuo LiangSpine Ward, Liuzhou People's Hospital, Liuzhou, People's Republic of China.ORCID 0000-0002-3003-416X
Jichong ZhuDepartment of Spine and Osteopathy Ward, the First Affiliated Hospital of Guangxi Medical University, Nanning, People's Republic of China.
Chenxing ZhouDepartment of Spine and Osteopathy Ward, the First Affiliated Hospital of Guangxi Medical University, Nanning, People's Republic of China.
Shaofeng WuDepartment of Spine and Osteopathy Ward, the First Affiliated Hospital of Guangxi Medical University, Nanning, People's Republic of China.
Yuanlin Yao *Department of Spine and Osteopathy Ward, the First Affiliated Hospital of Guangxi Medical University, Nanning, People's Republic of China.
Chengqian HuangDepartment of Spine and Osteopathy Ward, the First Affiliated Hospital of Guangxi Medical University, Nanning, People's Republic of China.
Bin ZhangDepartment of Spine and Osteopathy Ward, the First Affiliated Hospital of Guangxi Medical University, Nanning, People's Republic of China.
Sitan FengDepartment of Spine and Osteopathy Ward, the First Affiliated Hospital of Guangxi Medical University, Nanning, People's Republic of China.
Zequn WangDepartment of Spine and Osteopathy Ward, the First Affiliated Hospital of Guangxi Medical University, Nanning, People's Republic of China.
Shengsheng HuangDepartment of Spine and Osteopathy Ward, the First Affiliated Hospital of Guangxi Medical University, Nanning, People's Republic of China.
Xuhua SunDepartment of Spine and Osteopathy Ward, the First Affiliated Hospital of Guangxi Medical University, Nanning, People's Republic of China.
Liyi ChenDepartment of Spine and Osteopathy Ward, the First Affiliated Hospital of Guangxi Medical University, Nanning, People's Republic of China.
Xinli ZhanDepartment of Spine and Osteopathy Ward, the First Affiliated Hospital of Guangxi Medical University, Nanning, People's Republic of China.ORCID 0000-0002-6936-481X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The objective of this study was to utilize machine learning techniques to analyze perioperative factors and identify blood glucose levels that can predict the occurrence of surgical site infection following posterior lumbar spinal surgery. Methods: A total of 4019 patients receiving lumbar internal fixation surgery from an institute were enrolled between June 2012 and February 2021. First, the filtered data were randomized into the test and verification groups. Second, in the test group, specific variables were screened using logistic regression analysis, Lasso regression analysis, support vector machine, and random forest. Specific variables obtained using the four methods were intersected, and a dynamic model was constructed. ROC and calibration curves were constructed to assess model performance. Finally, internal model performance was verified in the verification group using ROC and calibration curves. Results: The data from 4019 patients were collected. In total, 1327 eligible cases were selected. By combining logistic regression analysis with three machine learning algorithms, this study identified four predictors associated with SSI, namely Modic changes, sebum thickness, hemoglobin, and glucose. Using this information, a prediction model was developed and visually represented. Then, we constructed ROC and calibration curves using the test group; the area under the ROC curve was 0.988. Further, calibration curve analysis revealed favorable consistency of nomogram-predicted values compared with real measurements. The C-index of our model was 0.986 (95% CI 0.981-0.994). Finally, we used the validation group to validate the model internally; the AUC was 0.987. Calibration curve analysis revealed favorable consistency of nomogram-predicted values compared with real measurements. The C-index was 0.982 (95% CI 0.974-0.999). Conclusion: Logistic regression analysis and machine learning were employed to select four risk factors: Modic changes, sebum thickness, hemoglobin, and glucose. Then, a dynamic prediction model was constructed to help clinicians simplify the monitoring and prevention of SSI.

Indexed as

blood glucosedynamic prediction modellumbar spine surgerymachine learningsurgical site infection

Identifiers

PMID37581167
PMCPMC10423613

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.