Evidence map›Paper›PMID 37581064›Full record

ArticleQuantitative imaging in medicine and surgery2023

CT-based deep learning segmentation of ovarian cancer and the stability of the extracted radiomics features.

Yiang Wang, Mandi Wang, Peng Cao, Esther M F Wong, Grace Ho, Tina P W Lam, Lujun Han, Elaine Y P Lee

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Article in Quantitative imaging in medicine and surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

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11citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  4. CT-based radiomics model to predict platinum sensitivity in epithelial ovarian carcinoma: a multicentre study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
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  6. Review
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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Yiang WangDepartment of Diagnostic Radiology, The University of Hong Kong, Hong Kong, China.
Mandi WangDepartment of Radiology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, China.
Peng CaoDepartment of Diagnostic Radiology, The University of Hong Kong, Hong Kong, China.
Esther M F WongDepartment of Radiology, Pamela Youde Nethersole Eastern Hospital, Hong Kong, China.
Grace HoDepartment of Radiology, Queen Mary Hospital, Hong Kong, China.
Tina P W LamDepartment of Radiology, Queen Mary Hospital, Hong Kong, China.
Lujun HanDepartment of Medical Imaging, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, China.
Elaine Y P LeeDepartment of Diagnostic Radiology, The University of Hong Kong, Hong Kong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Radiomics analysis could provide complementary tissue characterization in ovarian cancer (OC). However, OC segmentation required in radiomics analysis is time-consuming and labour-intensive. In this study, we aim to evaluate the performance of deep learning-based segmentation of OC on contrast-enhanced CT images and the stability of radiomics features extracted from the automated segmentation. Methods: Staging abdominopelvic CT images of 367 patients with OC were retrospectively recruited. The training and cross-validation sets came from center A (n=283), and testing set (n=84) came from centers B and C. The tumours were manually delineated by a board-certified radiologist. Four model architectures provided by no-new-Net (nnU-Net) method were tested in this task. The segmentation performance evaluated by Dice score, Jaccard score, sensitivity and precision were compared among 4 architectures. The Pearson correlation coefficient ( Results: The 3D U-Net cascade architecture achieved highest median Dice score, Jaccard score, sensitivity and precision for OC segmentation in the testing set, 0.941, 0.890, 0.973 and 0.925, respectively. Tumour volumes of manual and automated segmentations were highly correlated ( Conclusions: The presented deep-learning segmentation could provide highly accurate automated segmentation of OC on CT images with high stability of the extracted radiomics features, showing the potential as a batch-processing segmentation tool.

Indexed as

automated segmentationcomputed tomographydeep learningOvarian cancer (OC)radiomics

Identifiers

PMID37581064
PMCPMC10423396

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