ArticleQuantitative imaging in medicine and surgery2023
Can spectral computed tomography (CT) replace perfusion CT to assess the histological classification of non-small cell lung cancer?
Article in Quantitative imaging in medicine and surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed.
- Dielectric properties, thermal properties, blood perfusion rate: which biophysical parameter is the leading source of variability of microwave ablation models in lung?International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2026Article
- Application and Development of Spectral CT in Target Delineation for Lung Cancer Radiotherapy.Diagnostics (Basel, Switzerland) · 2026Review
- Advanced characterization and grading of invasive lung adenocarcinoma: integrative analysis with spectral CT andQuantitative imaging in medicine and surgery · 2026Article
- [Predicting Invasive Non-mucinous Lung Adenocarcinoma IASLC Grading: A Nomogram Based on Dual-energy CT Imaging and Conventional Features].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2025Article
- Differentiating pulmonary embolism from contrast accumulation-induced beam hardening artifacts using dual-energy CT quantitative parameters.Quantitative imaging in medicine and surgery · 2025Article
- Construction of a postoperative liver metastasis prediction model for colorectal cancer based on spectral CT imaging, CEA, and CA19-9.Translational cancer research · 2025Article
- Differentiation of pathological subtypes and Ki-67 and TTF-1 expression by dual-energy CT (DECT) volumetric quantitative analysis in non-small cell lung cancer.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024Article
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Abstract
Background: Non-small cell lung cancer (NSCLC) accounts for 80% of total lung cancer cases, it is necessary to distinguish the histological types of NSCLC. This study set out to investigate the correlation between spectral computed tomography (CT) and CT perfusion parameters in patients with NSCLC and to compare the differential diagnostic efficacy of these two imaging modalities for the histological classification of NSCLC. Methods: A total of 62 eligible consecutive patients, including 32 with lung adenocarcinoma (LUAD) and 30 with lung squamous cell carcinoma (LUSC), who underwent "one-stop" spectral combined perfusion scan and pathologically confirmed NSCLC at Lanzhou University Second Hospital between September 2020 and December 2021 were prospectively enrolled. The spectral parameters of lesions in the arterial phase (AP) and venous phase (VP) [including iodine concentration (IC), effective atomic number (Zeff), CT Results: BV and BF were strongly correlated with spectral parameters CT Conclusions: Spectral parameters are significantly correlated with perfusion parameters in NSCLC, and spectral CT has a better diagnostic efficacy than perfusion CT in differentiating the histological classification of NSCLC.
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