Evidence map›Paper›PMID 37580583›Full record

ArticleSurgical endoscopy2023

Role of short interval FLIP panometry in predicting long-term outcomes after per-oral endoscopic myotomy.

Jennifer M Kolb, Fernanda Pessorrusso, Sailaja Pisipati, Samuel Han, Paul Menard-Katcher, Rena Yadlapati, Mihir S Wagh

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgical endoscopy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Jennifer M KolbVatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at UCLA, Greater Los Angeles VA Healthcare System, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-6352-0797
Fernanda PessorrussoDivision of Gastroenterology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Sailaja PisipatiDivision of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, AZ, USA.
Samuel HanDivision of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Paul Menard-KatcherDivision of Gastroenterology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Rena YadlapatiDivision of Gastroenterology, University of California San Diego, San Diego, CA, USA.
Mihir S WaghDivision of Gastroenterology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. mihir.wagh@cuanschutz.edu.
University of Colorado Anschutz Medical Campus · USMayo Clinic in Arizona · USThe Ohio State University Wexner Medical Center · USUniversity of California San Diego · USVA Greater Los Angeles Healthcare System · US

Funding

GASTROINTESTINAL DISEASE TRAINING GRANTT32DK007038 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI COLGAN, SEAN P · 1986 to 2020
$3.5M
Mechanism Guided Therapy for Laryngopharyngeal RefluxK23DK125266 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI YADLAPATI, RENA HIREN · 2021 to 2025
$963k
NIDDK NIH HHS K23 DK125266NIDDK NIH HHS T32 DK007038NIH HHS K23 DK125266
6 · The paper itself

Abstract

backgroundThe Eckardt score (ES) is used to assess symptom response to Per-Oral Endoscopic Myotomy (POEM), but reliable methods to assess physiologic success are needed. Functional lumen imaging probe (FLIP) panometry has a potential role in post-POEM follow-up to predict long-term outcomes. The aim of this study was to assess the correlation between clinical success and FLIP parameters following POEM to determine if short interval FLIP could predict long-term outcomes.

methodsThis was a prospective study of adult patients who underwent POEM with short interval follow-up FLIP between 11/2017 and 3/2020. Clinical success was defined as post-procedure ES ≤ 3. Physiologic success was based on an esophago-gastric junction distensibility index (EGJ-DI) > 2.8 mm

results47 patients (55% female, mean age 55 years) were included in the study. Clinical success after POEM was seen in 45 (96%) patients (mean ES 6.5 ± 2.2 pre and 0.83 ± 1.0 post-POEM, p < 0.001). Physiologic success was noted in 43 (91.5%) patients (mean EGJ-DI 6.1 mm

conclusionPost-POEM endoscopy with FLIP is useful to both assess EGJ physiology and to examine for reflux esophagitis. Short interval FLIP has limited utility to predict long-term patient outcomes or risk of acid reflux.

Indexed as

Esophageal AchalasiaEsophagitis, PepticMyotomyNatural Orifice Endoscopic SurgeryAdultEsophageal Sphincter, LowerEsophagogastric JunctionFemaleHumansMaleMiddle AgedProspective StudiesTreatment OutcomeAchalasiaDysphagiaEsophageal manometryEsophagitis

Identifiers

PMID37580583
PMCPMC10771858
OpenAlexW4385803285

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.