Evidence map›Paper›PMID 37580526›Full record

ReviewBiological trace element research2024

What Are the Implications of Cr(III) Serving as an Inhibitor of the Beta Subunit of Mitochondrial ATP Synthase?

John B Vincent

Abstract readReview
PubMed Publisher
In one paragraph

Review in Biological trace element research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

John B VincentDepartment of Chemistry and Biochemistry, The University of Alabama, Tuscaloosa, AL, 35487-0336, USA. jvincent@ua.edu.

Funding

Molecular Structure of Chromium-DNA AdductsR15ES033800 · NIEHS · UNIVERSITY OF ALABAMA IN TUSCALOOSA · PI VINCENT, JOHN BERTRAM, WISE, JOHN PIERCE · 2022 to 2022
$434k
NIH HHS R15ES033800
6 · The paper itself

Abstract

A recent report has shown the active site of the beta subunit of mitochondrial ATP synthase is probably the site of action of Cr(III) action, independent of the insulin signaling pathway. This works appears to answer an important question about the mode of action of Cr(III) at a molecular level when supplied in supra-nutritional levels to rodents. However, as with any good research, the research also raises several questions. The relationship between this study and the results of rodent studies of chromium supplementation and between this study and the current understanding the chromium(III) transport and detoxification system are put into perspective.

Indexed as

InsulinMitochondrial Proton-Translocating ATPasesChromiumSignal TransductionChromiumInsulinMitochondrial Proton-Translocating ATPasesATP synthaseChromiumInsulin sensitivityTransport

Identifiers

PMID37580526

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.