ReviewMolecular psychiatry2023
Towards a youth mental health paradigm: a perspective and roadmap.
Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph
Review in Molecular psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07699159 (Cohort Network for Adolescents and Youth With multipLe Mental Health Conditions), which is not on this map. Cited by 159 papers, 7 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
159citing papers in PubMed, 7 pooled it
81.8field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cohort Network for Adolescents and Youth With multipLe Mental Health Conditions (CALM): A Master Observational Trial
Who cites it
159 citing papers in PubMed, 7 syntheses or guidelines pooled it, 262 citations in OpenAlex.
- The impact of premature birth and low birth weight on motor, visual, and cognitive skills and mental health in adolescence: a systematic review and meta-analysis.European child & adolescent psychiatry · 2026Pooled it
- Efficacy and safety of repetitive transcranial magnetic stimulation in youth with depression: a systematic review and meta-analysis of randomized sham-controlled trials.World journal of pediatrics : WJP · 2025Pooled it
- Early-stage profiles of adolescent mental health difficulties and well-being: A systematic review of cluster analyses in large school and community samples.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2025Pooled it
- Digital Mental Health Interventions for the Prevention and Treatment of Social Anxiety Disorder in Children, Adolescents, and Young Adults: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2025Pooled it
- Scoping review of precision child and youth mental health research: dwelling in possibility.Frontiers in psychiatry · 2025Pooled it
- Effectiveness of mHealth interventions targeting physical activity, sedentary behaviour, sleep or nutrition on emotional, behavioural and eating disorders in adolescents: a systematic review and meta-analysis.Frontiers in digital health · 2025Pooled it
- Psychological well-being and needs of parents and carers of children and young people with mental health difficulties: a quantitative systematic review with meta-analyses.BMJ mental health · 2024Pooled it
- Critical windows: timing of child maltreatment exposure and adult mental health.Child and adolescent psychiatry and mental health · 2026Article
- Pro-inflammatory markers interact with spontaneous theta oscillations to predict depression among adolescents.Brain, behavior, and immunity · 2026Article
- From innovation to integration: what German mental health professionals think about peer-led youth discovery colleges.European child & adolescent psychiatry · 2026Article
- Mental Health Support Services in Universities: A Dyadic Exploration of Students' and Counsellors' Perspectives.Healthcare (Basel, Switzerland) · 2026Article
- Identifiable regional and neural network abnormalities in early childhood anxiety.JCPP advances · 2026Article
- Neuroanatomy reflects individual variability in impulsivity in youth.Molecular psychiatry · 2026Article
- Mental health multimorbidity and physical conditions in children aged 6-17 years in the United States.General psychiatry · 2026Article
- Illuminating the complex interplay of risk factors for depression symptoms within a large-scale US longitudinal cohort.Social psychiatry and psychiatric epidemiology · 2026Article
- Brain rhythms of depression: A predictive processing perspective.Trends in neurosciences · 2026Review
- Differential adolescent neurodevelopment of emotion processing across internalizing psychopathology and childhood adversity.Developmental cognitive neuroscience · 2026Article
- Transdiagnostic child mental health trajectories in Japan: protocol for a nationwide web‑based open cohort study.BMC psychiatry · 2026Article
- Towards a neurobiology of early intervention: the importance of critical periods for preventive psychiatry and youth mental health.Molecular psychiatry · 2026Review
- Mental health outcomes in young adolescents born preterm reveal the need for earlier screening.European psychiatry : the journal of the Association of European Psychiatrists · 2026Article
99 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
37 authors at 20 institutions in 12 countries.
Peter J UhlhaasInstitute of Neuroscience and Psychology, University of Glasgow, Glasgow, UK. peter.uhlhaas@charite.de.ORCID 0000-0002-0892-2224
Christopher G DaveyDepartment of Psychiatry, The University of Melbourne, Carlton, VIC, Australia.ORCID 0000-0003-1431-3852
Urvakhsh Meherwan MehtaDepartment of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India.ORCID 0000-0002-2252-9189
Jai ShahDepartment of Psychiatry, McGill University, Montreal, QC, Canada.
John TorousDivision of Digital Psychiatry and Department of Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-5362-7937
Nicholas B AllenDepartment of Psychology, University of Oregon, Eugene, OR, USA.ORCID 0000-0002-1086-6639
Shelli AvenevoliOffice of the Director, National Institute of Mental Health, Bethesda, MD, USA.
Tolulope Bella-AwusahDepartment of Psychiatry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Andrew ChanenOrygen: National Centre of Excellence in Youth Mental Health, Parkville, VIC, Australia.
Eric Y H ChenDepartment of Psychiatry, University of Hong Kong, Hong Kong, China.
Christoph U CorrellDepartment of Child and Adolescent Psychiatry, Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Kim Q DoCentre for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital, Lausanne, Switzerland.ORCID 0000-0003-1968-1646
Helen L FisherSocial, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID 0000-0003-4174-2126
Sophia FrangouDepartment of Psychiatry, The University of British Columbia, Vancouver, BC, Canada.
Ian B HickieBrain and Mind Centre, University of Sydney, Camperdown, NSW, Australia.ORCID 0000-0001-8832-9895
Matcheri S KeshavanDepartment of Psychiatry, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-5945-888X
Kerstin KonradChild Neuropsychology Section, Department of Child and Adolescent Psychiatry, RWTH, Aachen, Germany.ORCID 0000-0001-9039-2615
Francis S LeeDepartment of Psychiatry, Weill Cornell Cornell Medicall College, New York, NY, USA.ORCID 0000-0002-7108-9650
Cindy H LiuDepartments of Pediatrics and Psychiatry, Brigham and Women's Hospital/Harvard Medical School, Boston, MA, USA.
Beatriz LunaDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Patrick D McGorryOrygen: National Centre of Excellence in Youth Mental Health, Parkville, VIC, Australia.
Andreas Meyer-LindenbergDepartment of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany.ORCID 0000-0001-5619-1123
Merete NordentoftCORE-Copenhagen Research Centre for Mental Health, Mental Health Center Copenhagen, University of Copenhagen, Faculty of Health and Medical Sciences, Department of Clinical Medicine, Hellerup, Denmark.
Dost ÖngürMcLean Hospital/Harvard Medical School, Belmont, MA, USA.
George C PattonCentre for Adolescent Health, Murdoch Children's Research Institute, University of Melbourne, Parkville, VIC, Australia.ORCID 0000-0001-5039-8326
Tomáš PausDepartments of Psychiatry and Neuroscience, Faculty of Medicine and Centre Hospitalier Universitaire Sainte Justine, University of Montreal, Montreal, QC, Canada.ORCID 0000-0003-1495-9338
Ulrich ReininghausDepartment of Public Mental Health, Central Institute of Mental Health, Medical Faculty Mannheim, Mannheim, Germany.
Akira SawaThe John Hopkins Schizophrenia Center, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0003-1401-3008
Michael SchoenbaumDivision of Service and Intervention Research, National Institute of Mental Health, Bethesda, MD, USA.
Gunter SchumannCentre for Population Neuroscience and Stratified Medicine, ISTBI, Fudan University, Shanghai, China.ORCID 0000-0002-7740-6469
Vinod H SrihariDepartment of Psychiatry, Yale University, New Haven, CT, USA.ORCID 0000-0003-1556-2332
Ezra SusserDepartments of Epidemiology and Psychiatry, Columbia University, New York, NY, USA.ORCID 0000-0001-7665-4826
Swapna K VermaDepartment of Psychosis, Institute of Mental Health, Buangkok, Singapore.
T Wilson WooDepartment of Psychiatry, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Lawrence H YangDepartment of Social and Behavioral Sciences, New York University, New York, NY, USA.
Alison R YungSchool of Medicine, Faculty of Health, Deakin University, Melbourne, VIC, Australia.ORCID 0000-0002-0401-9791
Stephen J WoodOrygen: National Centre of Excellence in Youth Mental Health, Parkville, VIC, Australia.
The University of Melbourne · AUBeth Israel Deaconess Medical Center · USKing's College London · GBBrigham and Women's Hospital · USCornell University · USDeakin University · AUDuke-NUS Medical School · SGFudan University · CNHarvard University · USHeidelberg University · DEHumboldt-Universität zu Berlin · DEJohns Hopkins University · USMcGill University · CANational Institute of Mental Health · USNational Institute of Mental Health and Neurosciences · INNew York Psychoanalytic Society and Institute · USNew York University · USNorthwell Health · USOffice of the Director · USRWTH Aachen University · DE
Funding
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9MNCATS NIH HHS UL1 TR001863
Abstract
Most mental disorders have a typical onset between 12 and 25 years of age, highlighting the importance of this period for the pathogenesis, diagnosis, and treatment of mental ill-health. This perspective addresses interactions between risk and protective factors and brain development as key pillars accounting for the emergence of psychopathology in youth. Moreover, we propose that novel approaches towards early diagnosis and interventions are required that reflect the evolution of emerging psychopathology, the importance of novel service models, and knowledge exchange between science and practitioners. Taken together, we propose a transformative early intervention paradigm for research and clinical care that could significantly enhance mental health in young people and initiate a shift towards the prevention of severe mental disorders.
Indexed as
Mental DisordersMental HealthAdolescentHumansPsychopathology
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
NCT07699159ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.